Protein Alignment KLK5 and CG4653

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 75/244 - (30%)
• Similarity: 117/244 - (47%)
• Gaps: 38/244 - (15%)

Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHC----------RKKVFRVR 117
            |||:    ..::.:||  .::.||.|.:: ||..|:..:|:||||||          ..|.:.||
  Fly    26 SSRL----PAEVGSQP--HSISLRRNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVR 84

Human   118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG--HSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
            :|  |:..:  :|.|:....|.|.|..||...  .||||.|::|...:....:..||::::..|:
  Fly    85 VG--SIQRL--TGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLATERPA 145

Human   181 AGTKCLVSGWGTTKSPQV--HFPKVLQCLNISVLSQKRCE-DAYPRQIDDTMFCAG----DKAGR 238
            ||::.:.||||   |.||  ....|||......||...|: :.|.:|.|  :.|..    |.||
  Fly   146 AGSQIIFSGWG---SSQVDGSLSHVLQVATRQSLSASDCQTELYLQQED--LLCLSPVDEDFAG- 204

Human   239 DSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
             .|.||:|.|...|..|.|:.::....|. ..:|..|.::.:..:||.|
  Fly   205 -LCSGDAGAPASYNNQLVGIAAFFVSGCG-SEQPDGYVDVTQHLEWINE 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/3 (100%)
		Tryp_SPc	66..285	CDD:214473	70/238 (29%)
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	72/236 (31%)