Protein Alignment KLK5 and CG9676

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_728008.1
• Gene: CG9676 / 32647
• FlyBaseID: FBgn0030773
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 78/296 - (26%)
• Similarity: 118/296 - (39%)
• Gaps: 65/296 - (21%)

Human     6 PPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIING 70
            |.|        |:||:.....|||.|| |...|                           ||:.|
  Fly     3 PFW--------TSLLVLCAAGVLAQND-SVVEP---------------------------RIVGG 31

Human    71 SDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKK--------VFRVRLGHYSLSPVY 127
            :.......|.|.:|..|.:.. ||..::...:::|||||.|:        ...::.|...||
  Fly    32 TKAREGQFPHQISLRRRGSHT-CGGSIISKDYVVTAAHCVKQGNNVAPANELEIQAGSLLLS--- 92

Human   128 ESGQQMFQGVKSIP------HPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 186
             ||     ||: :|      ||.|:..||  |:.:::|...:....::..|.:::..|.......
  Fly    93 -SG-----GVR-VPVATVTVHPNYNSNGH--DVAVLRLRNSLTFNSNIAAIKLATEDPPNDATVD 148

Human   187 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVC 251
            :||||.. |.:......|..:.:..||::.|:..|.||:.:|..|......:.:|.||||||...
  Fly   149 ISGWGAI-SQRGPISNSLLYVQVKALSRESCQKTYLRQLPETTMCLLHPKDKGACYGDSGGPATY 212

Human   252 NGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            .|.|.||.|:....|.|. .|..|..:.|...||.|
  Fly   213 QGKLVGLASFVIGGCGRA-APDGYERVSKLRNWIAE 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/30 (7%)
		Tryp_SPc	66..285	CDD:214473	63/232 (27%)
CG9676	NP_728008.1	Tryp_SPc	28..248	CDD:238113	65/235 (28%)