Protein Alignment KLK5 and CG8952

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Alignment Length: 238
• Identity: 60/238 - (25%)
• Similarity: 109/238 - (45%)
• Gaps: 18/238 - (7%)

Human    65 SRIINGSDCDMHTQPWQAALLLRP--NQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVY 127
            :||::|||..:...||| .:|.|.  :.|.||..::...|:||||||...:..:.| .:....::
  Fly    36 NRIVSGSDAKLGQFPWQ-VILKRDAWDDLLCGGSIISDTWVLTAAHCTNGLSSIFL-MFGTVDLF 98

Human   128 ESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN-VSSHCPS---AGTKCLVS 188
            .:..........|.||.|:.. .:||:.||:|...:..:.:::.|. |..:..|   .|:...::
  Fly    99 NANALNMTSNNIIIHPDYNDK-LNNDVSLIQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIA 162

Human   189 GWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ--IDDTMFCAG-DKAGRDSCQGDSGGPVV 250
            |:|.|:...:.:.:.|....:.::....|...|.:.  :|.||...| |.:...:|.||||||::
  Fly   163 GFGYTEDEYLDYSETLLYAQVEIIDNADCVAIYGKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLI 227

Human   251 C-NGSLQ-----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            . |.::|     |:.|:..........|..|..:..|..:|.:
  Fly   228 LYNKTIQQWQQIGINSFVAEDQCTYRLPSGYARVSSFLGFIAD 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	59/233 (25%)
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	59/233 (25%)