Protein Alignment KLK5 and CG33159

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_788455.1
• Gene: CG33159 / 318901
• FlyBaseID: FBgn0053159
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 88/296 - (29%)
• Similarity: 135/296 - (45%)
• Gaps: 63/296 - (21%)

Human     9 MWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDC 73
            :|.||.|  ||:|                     ||.|                |.:||:.|.:.
  Fly     7 LWWLCHL--ALVL---------------------PSSS----------------SKTRIVGGKET 32

Human    74 DMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSL---SPVYESG 130
            .:...|:  .:.||.|..: ||..|:..:.:|:||||    :.:.|.|..|...|   :||..:
  Fly    33 TISEVPY--LVYLRQNGYFICGGSLISSRAVLSAAHCVYGSQPEGFTVHAGASRLDQEAPVVRN- 94

Human   131 QQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRI--RPTKDVRPINVSSHCPSAGTKCLVSGWGTT 193
            ..||.     ..|.||......|:.|::|...:  .|.| |..|:...:.|.......:||||.|
  Fly    95 VVMFH-----TSPSYSATNFDMDVALLQLQEVVVLTPGK-VATISPCRNPPEGNAYARISGWGVT 153

Human   194 KSPQVHFPKVLQCLNISVLSQKRCEDAYP--RQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQ 256
            :.......:.::...:.||....|:.:|.  .|:.|:|.||..:..||||.||||||:|..|.:.
  Fly   154 RENNREPAEQVRTTMVRVLPGAECKISYSGYGQLSDSMLCAAVRGLRDSCSGDSGGPLVYRGQVC 218

Human   257 GLVSWGDYPCARPNRPGVYTNLC--KFTKWIQETIQ 290
            |:|||| :.||||:.||||||:.  :..::|::|::
  Fly   219 GIVSWG-FGCARPSFPGVYTNVASERVHEFIEQTLR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/30 (17%)
		Tryp_SPc	66..285	CDD:214473	75/232 (32%)
CG33159	NP_788455.1	Tryp_SPc	25..241	CDD:214473	75/225 (33%)