Protein Alignment KLK5 and CG32523

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_728401.1
• Gene: CG32523 / 318071
• FlyBaseID: FBgn0052523
• Length: 262
• Species: Drosophila melanogaster
• Alignment Length: 299
• Identity: 77/299 - (25%)
• Similarity: 118/299 - (39%)
• Gaps: 61/299 - (20%)

Human     9 MW-VLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSD 72
            || .|..::..||.||  .|:...||:.:...:.:                     ..||:.|..
  Fly     1 MWTTLWTVLLLLLCGV--QVILGQDVAQNQSESAI---------------------EPRIVGGIK 42

Human    73 CDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK--------KVFRVRLGHYSLS----- 124
            ......|.|.:|.|| .:.|||.|::....::||.||.|        .::.::.|...||
  Fly    43 AKQGQFPHQISLRLR-GEHYCGGVIISATHVITAGHCVKHGNDVVPADLWSIQAGSLLLSSDGVR 106

Human   125 -PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVS 188
             ||.|          .|.||.|:..|| |||.:::|...:....::..|.:::..|.......:|
  Fly   107 IPVAE----------VIMHPNYATGGH-NDLAVLRLQSPLTFDANIAAIQLATEDPPNCVAVDIS 160

Human   189 GWG--TTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVC 251
            |||  ..|.|   ....|..:.::.:|:..|...:..::.:||.|........:|.||||||...
  Fly   161 GWGNIAEKGP---LSDSLLFVQVTSISRGACRWMFYSRLPETMICLLHSKNSGACYGDSGGPATY 222

Human   252 NGSLQGLVS---WGDYPCARPNRPGVYTNLCKFTKWIQE 287
            .|.:.||.|   .|.  |.|. .|..|..:.|...||.|
  Fly   223 GGKVVGLASLLLGGG--CGRA-APDGYLRISKVRAWIAE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/30 (3%)
		Tryp_SPc	66..285	CDD:214473	64/237 (27%)
CG32523	NP_728401.1	Tryp_SPc	37..219	CDD:238113	51/196 (26%)