Protein Alignment KLK5 and CG32376

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 81/265 - (30%)
• Similarity: 128/265 - (48%)
• Gaps: 24/265 - (9%)

Human    38 PSNTVPSGSNQDLGAGAGEDARSDDSS--SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHP 100
            |.:..|:.:..::.:....:|.....|  :||:||........|:|.:|... ....||.|:::.
  Fly    35 PEDIAPTPNFGNISSNPFINALEAQESFPTRIVNGKRIPCTEAPFQGSLHYE-GYFVCGCVIINK 98

Human   101 QWLLTAAHC---RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRR 162
            .|:|||.||   ..:.:.||:|    |.....|.|:....|.:....|:.....:||.::||...
  Fly    99 IWILTAHHCFFGPPEKYTVRVG----SDQQRRGGQLRHVKKIVALAAYNDYTMRHDLAMMKLKSP 159

Human   163 IRPTKDVRPINVSSHCPSAGT-----KCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYP 222
            :...|.|||:.:    ||..|     |.:|||||.|.:...:..:.|:.:.|..:.:.:|:..|.
  Fly   160 VYFGKCVRPVKL----PSTKTTKFPKKFVVSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYK 220

Human   223 R---QIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKW 284
            :   :|...|.|| .:..:|||.||||||:...|.|.|:|||| ..||..|.||||.|..::..|
  Fly   221 KAGLKIYKDMICA-SRTNKDSCSGDSGGPLTSRGVLYGIVSWG-IGCANKNYPGVYVNCKRYVPW 283

Human   285 IQETI 289
            |::.|
  Fly   284 IKKVI 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/31 (16%)
		Tryp_SPc	66..285	CDD:214473	74/229 (32%)
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	74/229 (32%)