Protein Alignment KLK5 and CG32260

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_728942.1
• Gene: CG32260 / 317943
• FlyBaseID: FBgn0052260
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 282
• Identity: 94/282 - (33%)
• Similarity: 136/282 - (48%)
• Gaps: 46/282 - (16%)

Human    38 PSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAAL-LLRPN-----QLYCGAV 96
            |.|..|..|.....:||        :|:|::.|.:......||.||| ....|     :..||..
  Fly   307 PPNNAPRESATCGISGA--------TSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGS 363

Human    97 LVHPQWLLTAAHCRKKVFR-VRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLN 160
            |:|.::::|:|||...:.. ||||.:.||...|||....:..:::.|..:.....|||:.||:||
  Fly   364 LIHSRYVITSAHCINPMLTLVRLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELN 428

Human   161 RRIRPTKDVRPINVSSHC-PSA---------GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQK 215
                 .....|.|:|..| |.|         |....|:|||..|...| ..:||:...:.::|:.
  Fly   429 -----VVGALPGNISPICLPEAAKFMQQDFVGMNPFVAGWGAVKHQGV-TSQVLRDAQVPIVSRH 487

Human   216 RCEDAYPR-----QIDDTMFCAGDKAGRDSCQGDSGGPVV---CNGS-----LQGLVSWGDYPCA 267
            .||.:|..     |..|.:.||| .:..|:||||||||::   ..|:     |.||||:| |.||
  Fly   488 SCEQSYKSIFQFVQFSDKVLCAG-SSSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFG-YECA 550

Human   268 RPNRPGVYTNLCKFTKWIQETI 289
            |||.|||||.:..:..||::.|
  Fly   551 RPNFPGVYTRVASYVPWIKKHI 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/29 (28%)
		Tryp_SPc	66..285	CDD:214473	84/248 (34%)
CG32260	NP_728942.1	CLIP	194..244	CDD:463440
		Tryp_SPc	328..571	CDD:238113	85/250 (34%)