Protein Alignment KLK5 and CG3795

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_569939.2
• Gene: CG3795 / 31128
• FlyBaseID: FBgn0025378
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 274
• Identity: 80/274 - (29%)
• Similarity: 126/274 - (45%)
• Gaps: 34/274 - (12%)

Human    41 TVPSGSNQDLGAGAGEDA------RSDDSSSRIINGSDCDMH-TQPWQAALLL-RPNQL-----Y 92
            :|.:.||.:..||....|      |..|....:..|...|.: ...:..:|.: :|.:.     :
  Fly    14 SVSANSNSESQAGQLHSAPSQRQDRPSDFQFLVTGGYRPDTNDLVKYTVSLRMGKPKKFFGDNHF 78

Human    93 CGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSP---VYESGQQMFQGVKSIPHPGYSHPGH 150
            |...:...:.:||||||    |:|:...:|...:.:|   :..|..|:.:..:.:|||.|. .|.
  Fly    79 CAGTIFSERAILTAAHCMFSNRRKLKAKKLMVVAGTPRRLLKSSTTQIIEAEELLPHPKYK-KGK 142

Human   151 SN--DLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHF-PKVLQCLN--IS 210
            |.  |:.||.|...:.....|..|.:.:..|.||..|.:.||||.    :.| |...:.:|  :.
  Fly   143 SQKYDIGLILLEADLSLGDAVAKIPLYNKVPVAGAPCSIVGWGTV----IQFGPLPDEAINGDMQ 203

Human   211 VLSQKRCEDAYPRQIDDTMFCAGDK--AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPG 273
            :|....||...... :..|.||.||  :..||||||||||::|:..:.|:||:| ..|..|:..|
  Fly   204 ILPDTFCEKLLGWS-NAGMLCANDKHDSDVDSCQGDSGGPLICDNMVTGIVSFG-MGCGEPDSAG 266

Human   274 VYTNLCKFTKWIQE 287
            :||::..|..||.|
  Fly   267 IYTDVYHFRDWITE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		8/32 (25%)
		Tryp_SPc	66..285	CDD:214473	69/239 (29%)
CG3795	NP_569939.2	Tryp_SPc	60..281	CDD:238113	70/228 (31%)