Protein Alignment KLK5 and CG14780

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_569920.2
• Gene: CG14780 / 31102
• FlyBaseID: FBgn0025383
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 250
• Identity: 82/250 - (32%)
• Similarity: 120/250 - (48%)
• Gaps: 29/250 - (11%)

Human    61 DDSSSRIINGSDCDM-HTQPWQAALLLRPNQLY-----CGAVLVHPQWLLTAAHC----RKKVFR 115
            ::..|||||||.... .|:...:..|||.:..:     ||..|:.|:.:||||||    ::|.||
  Fly    27 ENQQSRIINGSVAKADETRHLVSIRLLRHDNNFGSGHICGGALIAPRKVLTAAHCLYNNQRKRFR 91

Human   116 ------VRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSND---LMLIKLNRRIRPTKDVR- 170
                  |.||  :|:........:...|.|:.:.....|....|   ::.::....:.|...|.
  Fly    92 RASEFVVVLG--TLNRFEHRNGTIVSQVSSMAYMHTFSPDSMRDDVGILFLRTGLPMSPGGGVHL 154

Human   171 ---PINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA 232
               ||.::......|..|.|:|||.|:  |.....:|...|:|.:..:.|...|...:...|.||
  Fly   155 TVAPIQLAGQITPPGKLCQVAGWGRTE--QSSLSNILLTANVSTIRHQTCRMIYRSGLLPGMMCA 217

Human   233 GD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286
            |. :.|.||||||||||:|..|.|.|:|||| |.||.|..||||.::..:.:||:
  Fly   218 GRLQGGTDSCQGDSGGPLVHEGRLVGVVSWG-YGCAEPGLPGVYVDVEYYRQWIE 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		2/6 (33%)
		Tryp_SPc	66..285	CDD:214473	79/242 (33%)
CG14780	NP_569920.2	Tryp_SPc	33..271	CDD:238113	79/242 (33%)