DRSC/TRiP Functional Genomics Resources

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Protein Alignment KLK5 and CG11664

DIOPT Version :10

Sequence 1:NP_036559.1 Gene:KLK5 / 25818 HGNCID:6366 Length:293 Species:Homo sapiens
Sequence 2:NP_569865.1 Gene:CG11664 / 31033 FlyBaseID:FBgn0040341 Length:254 Species:Drosophila melanogaster


Alignment Length:220 Identity:53/220 - (24%)
Similarity:96/220 - (43%) Gaps:39/220 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    88 PNQLYCGAVLVHPQWLLTAAHCRKK-----VFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH 147
            |..|..|: |...:::||.|||.||     ...||.|:..::  :|...:...|:  :.||.:|.
  Fly    43 PQFLAAGS-LFSARYVLTVAHCFKKNTKPEELSVRAGYRWIA--WEFRGKQVAGL--LRHPKFSP 102

Human   148 PGHSNDLMLIKLNRRI-------------RPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVH 199
            ....||:.::::...|             ||   :.|:|:.:. |..     ::||..     :|
  Fly   103 LTLRNDIAVLRVKAAISHSHMINYIGLCSRP---LTPLNMFAP-PQE-----LAGWNL-----MH 153

Human   200 FPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDY 264
            ..:.|:.:::.|..:|.|...:| ||...:.||....|...|.||||.|::..|.:.|| :....
  Fly   154 IAQPLKSMSVQVEPEKNCRQWFP-QISGGVICASATMGEGLCYGDSGDPLISGGEVCGL-AIAFR 216

Human   265 PCARPNRPGVYTNLCKFTKWIQETI 289
            .|.....|.::|::.....:|.:.:
  Fly   217 KCGDKRYPALFTDVHYHRAFIAQAV 241

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KLK5NP_036559.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 37..68
Tryp_SPc 66..285 CDD:214473 52/214 (24%)
CG11664NP_569865.1 Tryp_SPc 38..239 CDD:473915 53/216 (25%)
Blue background indicates that the domain is not in the aligned region.

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