Protein Alignment KLK5 and CG33459

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_995855.2
• Gene: CG33459 / 2768847
• FlyBaseID: FBgn0053459
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 265
• Identity: 82/265 - (30%)
• Similarity: 116/265 - (43%)
• Gaps: 68/265 - (25%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC---RKKVFRVRLGHY------ 121
            ||..|.|..:.:.||. |.|....|..||..|:..:::||||||   ..|...||||.|
  Fly    37 RIFGGMDAGLVSTPWM-AFLHNHLQFLCGGSLITSEFVLTAAHCVMPTPKNLTVRLGEYDWTRQM 100

Human   122 -SLSPVYESGQQMFQGVKSIPHPGYSHPGHSN----DLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
             |::|.:...:.|...:       |:||.:.:    |:.|:|||:.:..|..:|||
  Fly   101 DSINPKHRHREYMVTRI-------YTHPSYRSIAAYDIALLKLNQTVEYTVAIRPI--------- 149

Human   182 GTKCLV--------------------SGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQID 226
               |||                    :|||.||:..|  .:|||..|::.:.:..|.|.|...:|
  Fly   150 ---CLVLPENFHEWYWLVDSVEDFTLTGWGATKTEPV--SQVLQSANLTQIDRGTCHDRYGHSVD 209

Human   227 DTMFCAGDKAGRDSCQGDSGGP----VVCN----GSLQGLVSWGDYPCARPNRPGVYTNLCKFTK 283
            .|..|||.... .:|.||||.|    ||.|    .:..|:||.|...|   :...|:||:..||:
  Fly   210 HTHICAGSSKS-FACVGDSGSPLAMKVVHNRRYIHAQVGIVSRGPKNC---DGVTVFTNVVSFTE 270

Human   284 WIQET 288
            ||..|
  Fly   271 WIFRT 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	79/260 (30%)
CG33459	NP_995855.2	Tryp_SPc	37..272	CDD:214473	79/260 (30%)