Protein Alignment KLK5 and CG33458

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_995854.2
• Gene: CG33458 / 2768846
• FlyBaseID: FBgn0053458
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 273
• Identity: 76/273 - (27%)
• Similarity: 111/273 - (40%)
• Gaps: 75/273 - (27%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC----RKKVFRVRLGHYSLSPV 126
            ||..|.|..:...||.|.|.:. ::..||..|::..::||||||    ..||. ||||....|..
  Fly    37 RITGGRDSPLMLNPWLAYLHIN-SKFICGGSLLNHWFVLTAAHCFRDKNAKVL-VRLGENDASQK 99

Human   127 YESGQQ-------MFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
            .:..:.       .:..::.:.||.| ...|..|:.|.||||.:..|..:|||
  Fly   100 IDCNESECAAPHLEYMIMQKLIHPLY-RTAHYYDIALAKLNRYVVYTDSIRPI------------ 151

Human   185 CL-----------------VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA 232
            ||                 ::|||.|.:.:|  ...||...|..:.:..|...:...:|.|..||
  Fly   152 CLMLNPNWQVYVDTIRYFIITGWGATNASEV--SDKLQLTRIPQIDRFTCRYWFGYMVDRTHICA 214

Human   233 GDK---AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARP----------NRP----GVYTNLCK 280
            |:.   .|:    ||||||:   ||:.      ||..|:.          .:|    .|:||:..
  Fly   215 GESKHYVGK----GDSGGPL---GSMV------DYKYAKRFFQFGIVSHLRQPFHGVSVFTNILS 266

Human   281 FTKWIQETIQANS 293
            ::.||..||..||
  Fly   267 YSNWIHRTIITNS 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/1 (100%)
		Tryp_SPc	66..285	CDD:214473	70/263 (27%)
CG33458	NP_995854.2	Tryp_SPc	38..274	CDD:238113	71/265 (27%)