Protein Alignment KLK5 and CG33461

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_995843.3
• Gene: CG33461 / 2768840
• FlyBaseID: FBgn0053461
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 73/309 - (23%)
• Similarity: 124/309 - (40%)
• Gaps: 60/309 - (19%)

Human     9 MWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDC 73
            |..:.|.:...:|||  |  .::.|..:.....||.                  .|.:||||:..
  Fly     6 MKTIIAYLALFVLGV--H--GSSSVFLEENCGVVPR------------------LSYKIINGTPA 48

Human    74 DMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRV--RLGHYS------------LS 124
            .:...||. |.|..|....|...|::..::||:|||.:....:  |||..:            |.
  Fly    49 RLGRYPWM-AFLHTPTYFLCAGSLINQWFVLTSAHCIEDDVELIARLGENNRDNDIDCENNRCLE 112

Human   125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH-----CPSAGTK 184
            ...|....|.     ..|..|.....|||:.:::|.||:..|..::||.:..|     .....|.
  Fly   113 ATQEYNVDML-----FKHRLYDPKDFSNDIGMLRLERRVEYTYHIQPICIFHHRRMQLVVDQITW 172

Human   185 CLVSGWGTTKSP-QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGP 248
            ...:|||.|.:. .....:||..||:....:..|...:.:.......|||:..| :.|:||||||
  Fly   173 FKATGWGLTSTDLNTKSSRVLMELNLYRRPRNDCARIFKQNFLSGQICAGNDDG-NLCRGDSGGP 236

Human   249 ----VVCNGSLQ----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
                |:..|..:    |:.|:....|::.:   :.|::.::.:||::.:
  Fly   237 QGRYVLIFGMKRFVQMGIASFTYENCSKVS---ILTDVVRYGRWIKKVV 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		3/30 (10%)
		Tryp_SPc	66..285	CDD:214473	61/246 (25%)
CG33461	NP_995843.3	Tryp_SPc	41..278	CDD:214473	61/246 (25%)