Protein Alignment KLK5 and CG30287

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_726083.1
• Gene: CG30287 / 246530
• FlyBaseID: FBgn0050287
• Length: 284
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 79/258 - (30%)
• Similarity: 122/258 - (47%)
• Gaps: 41/258 - (15%)

Human    58 ARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR---KKVFRVRLG 119
            |||:....|:|||...|:.:.||...::.| ..:.||..|:.|:::||||||:   |....||||
  Fly    33 ARSEPGLYRVINGKPADLFSNPWMVIIIER-GMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLG 96

Human   120 HYSLSPVYESGQQMFQGVKSIPHPGYSH------PGH-----SNDLMLIKLNRRIRPTKDVRPIN 173
            .|.::...:.     .....||.|...:      |.|     .||:.|::|...::...::|.|.
  Fly    97 DYDVNQAVDC-----SSYGCIPRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSIC 156

Human   174 V-------SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFC 231
            :       ||:......|...:|||.|:| :::.| |||..:::......|...:.:|:|.:..|
  Fly   157 LLMGDYTWSSNILKNLVKFNTTGWGRTES-RINSP-VLQQASLTHHHLSYCAQVFGKQLDKSHIC 219

Human   232 AGDKAGRDSCQGDSGGPVVCN---GS-----LQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQ 286
            .....| .:||||||||:...   ||     |.|:||:|...|..|.   ||||:..|..||:
  Fly   220 VASSTG-STCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFGPT---VYTNVIHFANWIE 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		4/9 (44%)
		Tryp_SPc	66..285	CDD:214473	74/247 (30%)
CG30287	NP_726083.1	Tryp_SPc	42..280	CDD:238113	75/249 (30%)