Protein Alignment KLK5 and CG30091

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_725484.1
• Gene: CG30091 / 246449
• FlyBaseID: FBgn0050091
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 70/272 - (25%)
• Similarity: 118/272 - (43%)
• Gaps: 39/272 - (14%)

Human    50 LGAGAGEDARSDDSSS-------RIINGSDCDMHTQPWQAALLLRPN-QLYCGAVLVHPQWLLTA 106
            |.||.|.....|:...       :|:.|.|......||.|  |::.| :..||..::..:::|||
  Fly    13 LTAGRGSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMA--LIKTNDEFICGGSVITNKFVLTA 75

Human   107 AHC---------RKKVFRVRLGHYSLSPVYESG--QQMFQGVKSIPHPGYSHPGHSNDLMLIKLN 160
            |||         :.....|.||.|.|....|..  .:::...:...|..::...:.||:.|::|.
  Fly    76 AHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQ 140

Human   161 RRIRPTKDVRPINVSSHCPSAGTKCLVS-----GWGTTKSPQVHFPKVLQCLNISVLSQKRCEDA 220
            :.|.....::|:.:..:........|:.     |||.|.:.::  ...||.:.|..:.:|.||.|
  Fly   141 KSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKM--SNNLQMVKIYRIDRKMCEAA 203

Human   221 YPRQIDDTMFCAGDKAGRDSCQGDSGGPV--------VCNGSLQGLVSWGDYPCARPNRPGVYTN 277
            :....|..|||||...|||:|:.|||||:        :...:..|:||.|...|   ...|:||:
  Fly   204 FWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDC---RGFGMYTD 265

Human   278 LCKFTKWIQETI 289
            :.....:|:..:
  Fly   266 VMGHIDFIERIV 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		5/24 (21%)
		Tryp_SPc	66..285	CDD:214473	64/243 (26%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	64/243 (26%)
		Tryp_SPc	332..520	CDD:473915