Protein Alignment KLK5 and CG30083

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_725492.3
• Gene: CG30083 / 246444
• FlyBaseID: FBgn0050083
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 80/261 - (30%)
• Similarity: 133/261 - (50%)
• Gaps: 37/261 - (14%)

Human    43 PSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPN-----QLYCGAVLVHPQW 102
            |...:|.|....|    ..|.|.:|::|.:.:..|.||. |.:.:.|     :|.||..|:|.|:
  Fly    14 PGAMSQFLEPNCG----YPDISPKIMHGQNAENGTNPWM-AYIFKYNDKEVAELVCGGTLIHKQF 73

Human   103 LLTAAHC--RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRP 165
            :|:||||  |.::..||||.:|.|       :.|...|:..:..::...:|||:.::::...::.
  Fly    74 VLSAAHCIKRDQILAVRLGEHSSS-------RYFAVTKAFRNKYFTTGSYSNDIGILRIQPIVKF 131

Human   166 TKDVRPINV---SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD 227
            ...:|||.:   .:..|:..| ...:|||.|::..  |.|||:.:.::.|:...|.:.....:.:
  Fly   132 NAVIRPICIITDPTKVPNVKT-FKAAGWGKTENET--FSKVLKTVELNELNASECYNMLWVNVTE 193

Human   228 TMFCAGDKAGRDSCQGDSGGPVV----CNGSLQ----GLVSWGDYPCARPNRPGVYTNLCKFTKW 284
            :..|||...| |:|.||||||::    .:|||:    |::|:|...|   |.|||||.|..|..|
  Fly   194 SQICAGHPDG-DTCAGDSGGPLIHPVYMDGSLRYVQLGIISFGSSLC---NSPGVYTRLSSFIDW 254

Human   285 I 285
            |
  Fly   255 I 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		6/24 (25%)
		Tryp_SPc	66..285	CDD:214473	72/236 (31%)
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	72/235 (31%)