Protein Alignment KLK5 and CG30082

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001188942.1
• Gene: CG30082 / 246443
• FlyBaseID: FBgn0050082
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 81/252 - (32%)
• Similarity: 115/252 - (45%)
• Gaps: 47/252 - (18%)

Human    64 SSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKK--VFRVRLGHYSLS-- 124
            ::||:.|...|:.:.|| .|.|.:.:.|.|...|:..:::||||||...  :..||||.|..|
  Fly    37 TNRIVGGRTADIGSNPW-LAYLHKNSSLVCTGTLITKRFVLTAAHCLHSFHLLTVRLGEYDTSTR 100

Human   125 ---------PVYESGQQMFQGVKSIPHPGYSH------PGHSNDLMLIKLNRRIRPTKDVRPINV 174
                     |.||.        .|:.: .|.|      ....||:.|:|||..:.....:|||.:
  Fly   101 IDCTSEFCIPTYEE--------YSVEN-AYIHTFFGGRQDSRNDIGLLKLNGTVVYKLFIRPICL 156

Human   175 ---SSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKA 236
               ....|.:.| ...:|||  |...::...|||.:|:..|.|..||.:....:....||||...
  Fly   157 FRDPGQVPYSST-YEAAGWG--KIDLINTATVLQTVNLIRLDQSDCERSLRTSLSYGQFCAGQWR 218

Human   237 GRDSCQGDSGGPV---VCNGSLQ-----GLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            . |:|.||||||:   :.||.:.     |:||:|.|.|   ..|||||.:..||.||
  Fly   219 A-DTCSGDSGGPLSRKMSNGRITRTVQLGIVSYGHYLC---RGPGVYTYVPSFTNWI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/3 (33%)
		Tryp_SPc	66..285	CDD:214473	79/248 (32%)
CG30082	NP_001188942.1	Tryp_SPc	40..274	CDD:238113	80/249 (32%)