Protein Alignment KLK5 and CG43336

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 77/289 - (26%)
• Similarity: 119/289 - (41%)
• Gaps: 82/289 - (28%)

Human    45 GSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC 109
            ||.|.|....|..|.| .|..|:.||:...:.:.||.|.|.....:..||..|:..:.:||||||
  Fly    17 GSTQFLDMACGIRAHS-PSVPRVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLTAAHC 80

Human   110 ---RKKVFRVRLGHYSLSPVYESGQQMF--QGVKSIPHPGYSHPGHSN------DLMLIKLNRRI 163
               |.::. .|||.|.... ||.....:  ..::::...|:.| .|.|      |:.:::|.|::
  Fly    81 FLDRTELV-ARLGEYDREE-YEMCHDSYCTYRIEAMVERGFRH-RHYNPMTMAYDIAILRLYRKV 142

Human   164 RPTKDVRPI----------NVSSHCPSAGTKCLVSGWGTTKS----------------PQVHFPK 202
            :.|.::|||          .:.|..|..||     |||.|:|                |:|
  Fly   143 QYTDNIRPICIVIDPRWRKYIDSLDPLTGT-----GWGKTESEGDSAKLRTVDLARKHPEV---- 198

Human   203 VLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSL-----------Q 256
               |...:.||           :....||||::.. :.|.|||||||   |:|           .
  Fly   199 ---CRRYATLS-----------LTANQFCAGNERS-NLCNGDSGGPV---GALIPYGKSKRFVQV 245

Human   257 GLVSWGDYPCARPNRPGVYTNLCKFTKWI 285
            |:.|:.:..|...:   |:|::..:..||
  Fly   246 GIASFTNTQCVMVS---VFTDVMSYVDWI 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		9/22 (41%)
		Tryp_SPc	66..285	CDD:214473	67/266 (25%)
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	67/266 (25%)