Protein Alignment KLK5 and CG43335

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001247121.1
• Gene: CG43335 / 12798413
• FlyBaseID: FBgn0263040
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 251
• Identity: 80/251 - (31%)
• Similarity: 122/251 - (48%)
• Gaps: 40/251 - (15%)

Human    65 SRIINGSDCDMHTQPWQAALLLRPNQL--YCGAVLVHPQWLLTAAHC--RKKVFRVRLGHYSLSP 125
            :|||.|||.::.:.||.|.|.   |:.  :|...|:..|::||||||  ..|...||||...|:.
  Fly    40 TRIIGGSDAEITSHPWMAYLY---NEFHYFCAGTLITNQFVLTAAHCIEASKNLTVRLGGSGLTR 101

Human   126 VYESGQQM----FQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC----PSA- 181
            ...|..|:    :....:|.|..::.....||:.:|:|.|.::....:|||     |    |:.
  Fly   102 SDGSMCQITAEDYSVSMAIKHKYFTPSIMLNDIAMIRLARTVKFYDHIRPI-----CIILDPAVR 161

Human   182 -----GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSC 241
                 |...:.:|||.. ..::| |.:||...|:|:::..|...|...|.....|||||. .::|
  Fly   162 LLLEDGMTLMATGWGLA-DKRMH-PHLLQEAPITVMNRNVCSKLYDVAITQGQICAGDKE-TNTC 223

Human   242 QGDSGGPV--VCN--GSLQ----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETI 289
            .||||||:  |.|  |.|:    |:.|:||..|   ..|.:||:|..::.||...:
  Fly   224 LGDSGGPLGGVVNYYGDLRFVQYGITSFGDIEC---RSPSIYTDLSTYSGWINMVV 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	78/244 (32%)
CG43335	NP_001247121.1	Tryp_SPc	42..275	CDD:238113	79/246 (32%)