Protein Alignment KLK5 and CG43110

DIOPT Version :10

• Sequence 1: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Sequence 2: NP_001246396.1
• Gene: CG43110 / 12798330
• FlyBaseID: FBgn0262570
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 65/240 - (27%)
• Similarity: 119/240 - (49%)
• Gaps: 28/240 - (11%)

Human    66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRK-KVFRVRLGHYSLS-PVYE 128
            :||:||:....:..:.|. :.....|.||..::|..::||.|||:. :...||||.|::: |.
  Fly    35 KIISGSNASQQSAQYMAG-IFNTTHLLCGGTIIHEDFVLTVAHCKSTQTLFVRLGAYNINHPT-- 96

Human   129 SGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL----VSG 189
               ...:.:::|.||.||:..::||:.|:||.|.:....:::||.:  |..:...|.:    ..|
  Fly    97 ---DQIRVIETIAHPQYSNSTYANDIALVKLERSVIFNLNIQPICI--HLDATLGKQIRYYNAFG 156

Human   190 WGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGS 254
            ||.|::.:.  ..:||.:.::..:...|........|....||....| |:|.||||||::...:
  Fly   157 WGRTRNAEQ--SDILQRIFVNRTNPMICHLYLGMSPDPKQICATTDQG-DTCAGDSGGPLISKIT 218

Human   255 LQ--------GLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
            .|        |:.|:|...|   |..|:||::.:::.||...:::
  Fly   219 YQGKNFDTQFGITSYGTREC---NGVGLYTDVSQYSGWIANIVRS 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		0/1 (0%)
		Tryp_SPc	66..285	CDD:214473	63/232 (27%)
CG43110	NP_001246396.1	Tryp_SPc	36..257	CDD:238113	65/234 (28%)