DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC39A6 and Zip48C

DIOPT Version :9

Sequence 1:	NP_036451.4	Gene:	SLC39A6 / 25800	HGNCID:	18607	Length:	755	Species:	Homo sapiens
Sequence 2:	NP_610712.1	Gene:	Zip48C / 36273	FlyBaseID:	FBgn0033665	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	172	Identity:	42/172 - (24%)
Similarity:	75/172 - (43%)	Gaps:	23/172 - (13%)

- Green bases have known domain annotations that are detailed below.

Human   585 EELKDAGVATLAW----MVIMGDGLHNFSDGLAIGAAF-------TEGLSSGLSTSVAVFCHELP 638
            ||.:.|..|...|    ::::...:||..:|||:|.:|       :....|..:.::.:.....|
  Fly   178 EEQQRAEDALSQWKRIMLLVVAITVHNIPEGLAVGVSFGAIGSTNSSTFESARNLAIGIGIQNFP 242

Human   639 HELGDFAVLLKAGMTVKQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALV 703
            ..|.....|..||.:||:|:.|..||.|:..:....|.....:|..:..:..:..||..:|:...
  Fly   243 EGLAVSLPLHAAGFSVKRALWYGQLSGMVEPIFGVLGAVAVTFANLILPYALSFAAGAMIYIVSD 307

Human   704 DMVPEMLHNDASDHG-CSRWGYFFLQNAGMLLGFGIMLLISI 744
            |::||.   .||.:| .:.|        |.:.||.||:.:.:
  Fly   308 DILPEA---HASGNGTIATW--------GTVSGFLIMMCLEV 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A6	NP_036451.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	95..186
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..246
		Zip	323..742	CDD:308248	42/168 (25%)
Zip48C	NP_610712.1	ZupT	23..340	CDD:223505	42/172 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810