DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZNF324 and CG10654

DIOPT Version :9

Sequence 1:XP_005258770.1 Gene:ZNF324 / 25799 HGNCID:14096 Length:558 Species:Homo sapiens
Sequence 2:NP_001261767.1 Gene:CG10654 / 39428 FlyBaseID:FBgn0036294 Length:412 Species:Drosophila melanogaster


Alignment Length:226 Identity:71/226 - (31%)
Similarity:102/226 - (45%) Gaps:32/226 - (14%)


- Green bases have known domain annotations that are detailed below.


Human   229 MGAVWQEPHRLLGGQEPSTWDELG-EALHAGEK------------SFECRACSKVFVKSSDLLKH 280
            :||..:|...::  ::.|...:|| |.|....|            :.|||.|.:.|.|.|.|..|
  Fly   182 LGASLEEEVYVI--EDESAKQDLGQEKLSISSKLLGARKRRGVRHTLECRICHRGFYKPSLLEAH 244

Human   281 LRTHTGERPYECAQCGKAFSQT----SHLTQ-HQRIHSGETPYACPVCGKAFRHSSSLV-----R 335
            ::.|.|.|||.|..|.|::::.    |||.| |....:....||||.|.|.:..:.||.     .
  Fly   245 MQQHEGLRPYTCVHCAKSYARANLLESHLRQMHNNADAARIIYACPSCNKVYTANRSLKYHMRRT 309

Human   336 HQRIHTAEK---SFRCSECGKAFSHGSNLSQHRKIHAG--GRPYACAQCGRRFCRNSHLIQHERT 395
            |:|.|.:|.   ...|.||||.|:..::|::|:.:|..  ||.|.|..|.|||....:::.|...
  Fly   310 HERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEGRRYCCECCDRRFYTKENMVDHLLR 374

Human   396 HTGEKPFV--CALCGAAFSQGSSLFKHQRVH 424
            ..|.|..:  |..||..|.....|..|.|.|
  Fly   375 KHGNKNLLLRCRKCGRIFQNSVELNAHGRKH 405

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZNF324XP_005258770.1 KRAB 6..66 CDD:214630
KRAB 6..45 CDD:279668
C2H2 Zn finger 264..284 CDD:275368 8/19 (42%)
COG5048 <268..468 CDD:227381 58/174 (33%)
zf-H2C2_2 276..301 CDD:290200 10/24 (42%)
C2H2 Zn finger 292..312 CDD:275368 8/24 (33%)
zf-H2C2_2 304..329 CDD:290200 10/25 (40%)
C2H2 Zn finger 320..340 CDD:275368 8/24 (33%)
zf-H2C2_2 332..357 CDD:290200 12/32 (38%)
C2H2 Zn finger 348..368 CDD:275368 8/19 (42%)
zf-C2H2 374..396 CDD:278523 7/21 (33%)
C2H2 Zn finger 376..396 CDD:275368 6/19 (32%)
zf-H2C2_2 388..413 CDD:290200 7/26 (27%)
C2H2 Zn finger 404..424 CDD:275368 7/19 (37%)
zf-H2C2_2 416..441 CDD:290200 4/9 (44%)
C2H2 Zn finger 432..452 CDD:275368
COG5048 437..>524 CDD:227381
zf-H2C2_2 444..468 CDD:290200
C2H2 Zn finger 460..480 CDD:275368
zf-H2C2_2 473..495 CDD:290200
C2H2 Zn finger 488..508 CDD:275368
CG10654NP_001261767.1 zf-AD 39..115 CDD:285071
C2H2 Zn finger 228..248 CDD:275368 8/19 (42%)
C2H2 Zn finger 256..313 CDD:275368 17/56 (30%)
C2H2 Zn finger 289..314 CDD:275368 8/24 (33%)
zf-C2H2 323..345 CDD:278523 8/21 (38%)
C2H2 Zn finger 325..345 CDD:275368 8/19 (42%)
C2H2 Zn finger 355..376 CDD:275368 6/20 (30%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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