Protein Alignment FSCN2 and sn

DIOPT Version :10

• Sequence 1: NP_001070650.1
• Gene: FSCN2 / 25794
• HGNCID: 3960
• Length: 516
• Species: Homo sapiens
• Sequence 2: NP_511076.3
• Gene: sn / 31717
• FlyBaseID: FBgn0003447
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 187/512 - (36%)
• Similarity: 286/512 - (55%)
• Gaps: 37/512 - (7%)

Human    15 GLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVAC 79
            ||:|...:|:|||:||||:||:..|||:||.|.|||. ..|.:::...|||.:|||.::.|.|.|
  Fly    28 GLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPS-NTGESIIYLRSHLNKYLSVDQFGNVLC 91

Human    80 EAEQPGRDCRFLVLPQPD--GRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAH 142
            |:::.....||.:....|  |||.|::|..|.|.|||.|:|.|.|.....:|.||||||..||.:
  Fly    92 ESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVN 156

Human   143 LLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSR---RYCLKSCDSRYLRSDGRLVWEP 204
            |.|:.|:|:.||...:||:..|.:.|||.|.|.||.||:.   ||.|.:|:::||.::|:|....
  Fly   157 LRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVC 221

Human   205 EPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAA-NH 268
            .....::.|:..|.||.:|..|.||:|:|....||: |::...:||||.||:|.||...:|. |.
  Fly   222 NEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNL 285

Human   269 RYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTM 333
            |||||:|||:|:||||:..::|||.::.|....:....::...||.|...|||.||..:..|:.:
  Fly   286 RYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADAL 350

Human   334 FEMEWRG-RRVALKASNGRYVCMKKNGQLAAISDFVGPPPRPAWTGKVAGGAAQQTLSPPGKDEE 397
            ||:.|.| ..::.:|:||:::..|::|.|.|.|:.:         .::|               :
  Fly   351 FELIWHGDGSLSFRANNGKFLATKRSGHLFATSESI---------EEIA---------------K 391

Human   398 FTLKLINRPILVLRGLDGFVCHHR-GSNQLDTNRSVYDVFHLSFSD-GAYRIRGRDGGFW-YTGS 459
            |...|||||||||:...|||.:.. |:.:|:.|::.|:...:..:. |...::...|.:| ..|.
  Fly   392 FYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGE 456

Human   460 HGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY 516
            ..||.:|.. ::.|..|.||..|:.||::.||||....:|..:...|.......||:
  Fly   457 SISVDADAP-SDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FSCN2	NP_001070650.1	beta-trefoil_FSCN2_rpt1	7..137	CDD:467453	56/123 (46%)
		beta-trefoil_FSCN2_rpt2	138..256	CDD:467457	46/120 (38%)
		beta-trefoil_FSCN-like	258..404	CDD:483951	45/147 (31%)
		beta-trefoil_FSCN2_rpt4	405..516	CDD:467465	34/113 (30%)
sn	NP_511076.3	beta-trefoil_singed_rpt1	22..151	CDD:467455	56/123 (46%)
		beta-trefoil_singed_rpt2	152..272	CDD:467459	46/120 (38%)
		beta-trefoil_singed_rpt3	274..398	CDD:467463	45/147 (31%)
		beta-trefoil_singed_rpt4	399..512	CDD:467467	34/113 (30%)