Protein Alignment SNX33 and snx33

DIOPT Version :10

• Sequence 1: NP_695003.1
• Gene: SNX33 / 257364
• HGNCID: 28468
• Length: 574
• Species: Homo sapiens
• Sequence 2: NP_001016368.1
• Gene: snx33 / 549122
• XenbaseID: XB-GENE-955365
• Length: 549
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 419/576 - (72%)
• Similarity: 476/576 - (82%)
• Gaps: 29/576 - (5%)

Human     1 MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVRSGIST 65
            ||||.||||.|..||||||:|.::|:|.:||:.||||||||.||||:|||||||||||:|....:
 Frog     1 MALKARALYSFQGENKEEINILENEELHLFSDVSLDGWLQGTNSRGQTGLFPASYVEILRPRSGS 65

Human    66 NHADYSSSPAGSPGAQVSLYNSPSVASPARSGGGSGFLSNQGSFEED--DDDDWDDWDDGCTVVE 128
            ...|||....|       ..:||                :|||:::|  |||||||||||.|||:
 Frog    66 VQVDYSGHTQG-------YTDSP----------------HQGSYDDDEEDDDDWDDWDDGQTVVD 107

Human   129 EPRAGGLGTNGHPPLNLSYPGAYPSQHMAFRPKPPLERQDSLASAKRGSVVGRNLNRFSCFVRSG 193
            ||.    |:||.....|.:...||......||:|.||||||:||.||||||||||||||.|||||
 Frog   108 EPS----GSNGVSRSQLQHHHHYPRPEYTHRPRPALERQDSIASGKRGSVVGRNLNRFSSFVRSG 168

Human   194 VEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIKSYISYKLTPTH 258
            ||||:|||||....::|:::|||||:||||||||.||:||||:||||||||||||||||:|||..
 Frog   169 VEAFVLGDVPQFGGVSESHAIEMGPKGPQWKANPRPFSCSVEEPTKQTKFKGIKSYISYRLTPDP 233

Human   259 AASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRKRRLILWMDHMTSHPVL 323
            ..|||||||||||||||||||||||||||||||||||||||||||:||||||:||||||||||||
 Frog   234 CNSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIQKRKRRLVLWMDHMTSHPVL 298

Human   324 SQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTEHQDLQDVEDRVDTFKAFSKKM 388
            |||:||||||||.|:||||.||||||:||:||||||||.|:|||||||||||:|||.||||||||
 Frog   299 SQYDGFQHFLSCQDEKQWKAGKRRAERDELVGASFLLTLQLPTEHQDLQDVEERVDVFKAFSKKM 363

Human   389 DDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSEALNSAISHTGRTYEAI 453
            |::|||||:|.|||.|||:||||||||:||:|.|.:|||||:|||:.||.|..|||||||||||:
 Frog   364 DENVLQLSSVVSELARKHLGGFRKEFQRLGAALQGLSHSFQLDPPYSSEPLVGAISHTGRTYEAV 428

Human   454 GEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRR 518
            |||||||||||.|:.||||||||||||||||||||||||||||||||||||||||.||||||||:
 Frog   429 GEMFAEQPKNDQFRFLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMEQDEADGIRK 493

Human   519 RCRVVGFALQAEMNHFHQRRELDFKHMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574
            ||||||||||||:|||||||..|||..:|:||::|||||:||.|:|||||.|||:|
 Frog   494 RCRVVGFALQAEINHFHQRRLQDFKQAIQHYLKEQILFYRRVSQELEKTLHMYDDL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SNX33	NP_695003.1	SH3_SNX33	4..58	CDD:212829	38/53 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..119		15/52 (29%)
		PX_domain	230..354	CDD:470617	109/123 (89%)
		BAR_SNX33	365..571	CDD:153353	167/205 (81%)
snx33	NP_001016368.1	SH3	4..58	CDD:473055	38/53 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..137		34/97 (35%)
		PX_domain	205..329	CDD:470617	109/123 (89%)
		BAR	340..546	CDD:472257	167/205 (81%)