Protein Alignment NEGR1 and dpr17

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001287297.1
• Gene: dpr17 / 41470
• FlyBaseID: FBgn0051361
• Length: 664
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 68/260 - (26%)
• Similarity: 105/260 - (40%)
• Gaps: 65/260 - (25%)

Human    47 NMMVRKGDTAVLRCYLEDGASKG-AW--LNRSSIIFAGGDKWSVDPRVSISTLNKRDY--SLQIQ 106
            |:..:.|:.|.:.|.:...:.|. :|  :..:.||......:..|.|.........||  ||||:
  Fly   414 NITAQMGNHAYMPCQIHRLSDKPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIK 478

Human   107 NVDVTDDGPYTCSVQTQHTPR-TMQVHLTVQVPPKIYDISNDMT--VNEGTNVTLTCLATGKPEP 168
            .|:.:|.|.|.|.:.|:  |: :.:|||.: |.||. ::..|.:  |..|:.|.|.|:..|..:|
  Fly   479 YVEPSDAGWYECQMATE--PKLSAKVHLQI-VKPKT-ELIGDQSRFVKAGSKVALHCIVRGTLDP 539

Human   169 S--ISW----RHISPSAKPFENGQY--LD--IYG----------------ITRDQAGEYECSAEN 207
            .  |.|    :.||.|.:  ..|.|  ||  |:|                :.::.:|.|.|...|
  Fly   540 PKYIIWFRGQKKISDSDE--RTGWYTQLDRNIFGTVGDNQNTIGSLIIPLVRKEDSGNYTCQPSN 602

Human   208 DVSFPDVRKVKVVVNF------APTIQEIKSGTVTPGRS------------GLI-RCEGAGVPPP 253
            .||      |.|.::.      |..|....:.|...|||            ||: ..:||...||
  Fly   603 SVS------VSVDLHVLSGEYSASAIMSTAARTTKGGRSTCHSTLGLLGILGLLWAMQGAMHTPP 661

Human   254  253
              Fly   662  661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	26/93 (28%)
		IGc2	152..210	CDD:197706	21/83 (25%)
		Ig_3	225..301	CDD:372822	11/42 (26%)
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	20/76 (26%)
		Ig	415..507	CDD:299845	25/94 (27%)
		IG_like	521..612	CDD:214653	26/98 (27%)
		IGc2	524..605	CDD:197706	21/82 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810