Protein Alignment NEGR1 and dpr16

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001287169.1
• Gene: dpr16 / 40619
• FlyBaseID: FBgn0037295
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 312
• Identity: 63/312 - (20%)
• Similarity: 101/312 - (32%)
• Gaps: 117/312 - (37%)

Human    47 NMMVRKGDTAVLRCYLEDGASKG-AW--LNRSSIIFAGGDKWSVDPR-------VSISTL----- 96
            |..|:.|..|.|.|.|...:.|. :|  |....||......:..|.|       .:::||
  Fly   207 NATVQAGQHAYLPCKLNQHSGKPLSWVRLRDEHIIAVDHTTFINDARFASLLQSTTLTTLVSGGA 271

Human    97 ----------------------------NKRDYSLQIQNVDVTDDGPYTCSVQTQHTPR-TMQVH 132
                                        :...::|||:.|::.|.|.|.|.:.|:  |: :.:|.
  Fly   272 LSTTATPVAALGNSFAHAVPGGQERGNSSSLSWTLQIKYVNLEDAGWYECQLATE--PKMSAKVQ 334

Human   133 LTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQ 197
            |.|..|...........|..|:.|.|.|:..|                ..|..:|:..|
  Fly   335 LFVITPRTELIGDRQRFVKAGSRVELHCIVRG----------------TLEAPKYIFWY------ 377

Human   198 AGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWY-KGE 261
            .|:.:.:|||:.|                          ..:||               || :.:
  Fly   378 RGDQQVTAENEAS--------------------------GAQSG---------------WYTQID 401

Human   262 KKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
            :.:|...:    .|.:|...|.:..|.:.|.|||||...|   :..||:.|:
  Fly   402 RNIFGSTE----HNRNTIGSLVIPLVRKIHSGNYTCEPEN---SAAASMQLH 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	28/131 (21%)
		IGc2	152..210	CDD:197706	12/57 (21%)
		Ig_3	225..301	CDD:372822	15/76 (20%)
dpr16	NP_001287169.1	IG_like	205..337	CDD:214653	28/131 (21%)
		Ig	<298..338	CDD:299845	12/41 (29%)
		IG_like	352..447	CDD:214653	33/165 (20%)
		Ig	358..439	CDD:143165	28/150 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810