Protein Alignment NEGR1 and dpr10

DIOPT Version :10

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_729591.1
• Gene: dpr10 / 39180
• FlyBaseID: FBgn0052057
• Length: 408
• Species: Drosophila melanogaster
• Alignment Length: 369
• Identity: 76/369 - (20%)
• Similarity: 115/369 - (31%)
• Gaps: 153/369 - (41%)

Human    29 PSCLPAGQSVDFPWAAVDNMMVRK-----GDTAVLRCYLED-GASKGAWLNRSS--IIFAGGDKW 85
            ||..|.|...:.|:  .|..|.|.     |.:|.|.|.::. |....||:....  |:..|...:
  Fly    41 PSHYPHGHKWNEPY--FDLTMPRNITSLVGKSAYLGCRVKHLGNKTVAWIRHRDLHILTVGTYTY 103

Human    86 SVDPRVSISTLNKRD---YSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQ----------- 136
            :.|.|  ..|...||   ::|||:.....|.|.|.|.:.||.. |:..|:|.:.
  Fly   104 TTDQR--FQTSYHRDIDEWTLQIKWAQQRDAGVYECQISTQPV-RSYSVNLNIVDLIDAETSDIM 165

Human   137 -----------VPPKIYDISN------------------------DMTVNEGTNVTLTCLATGKP 166
                       ...::|..||                        |:.|::|:.:.|||:....|
  Fly   166 QQYYNDDAFYIAENRVYQSSNDEFAGMFGPIQTVAVPTATILGGPDLYVDKGSTINLTCIIKFSP 230

Human   167 EP--SISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQE 229
            ||  .|.|.|                    :|:                            .:.|
  Fly   231 EPPTHIFWYH--------------------QDK----------------------------VLSE 247

Human   230 IKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGN 294
            ..||    ||.             .|:..|.|:               |:|||.:.:....|.|.
  Fly   248 ETSG----GRL-------------KFKTIKSEE---------------TKSILLIYDADLLHSGK 280

Human   295 YTCVAANKLGTTNASLPLN-----PPSTAQYGITGSADVLFSCW 333
            |:|..:|   |..||:.::     .|...|.....:| |..:||
  Fly   281 YSCYPSN---TEIASIRVHVLQGERPEAMQTNAAPAA-VALACW 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG_like	47..135	CDD:214653	28/98 (29%)
		Ig strand B	56..60	CDD:409353	2/3 (67%)
		Ig strand C	68..72	CDD:409353	1/3 (33%)
		Ig strand E	101..105	CDD:409353	1/3 (33%)
		Ig strand F	115..120	CDD:409353	2/4 (50%)
		Ig strand G	128..131	CDD:409353	0/2 (0%)
		Ig_3	138..207	CDD:464046	16/94 (17%)
		IG_like	231..312	CDD:214653	19/80 (24%)
		Ig strand B	241..245	CDD:409353	0/3 (0%)
		Ig strand C	254..258	CDD:409353	1/3 (33%)
		Ig strand E	280..284	CDD:409353	3/3 (100%)
		Ig strand F	294..299	CDD:409353	2/4 (50%)
dpr10	NP_729591.1	Ig	53..138	CDD:472250	24/88 (27%)
		Ig strand B	71..75	CDD:409371	2/3 (67%)
		Ig strand E	120..124	CDD:409371	1/3 (33%)
		Ig_3	214..287	CDD:464046	28/152 (18%)