Protein Alignment NEGR1 and ImpL2

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_728961.2
• Gene: ImpL2 / 38513
• FlyBaseID: FBgn0001257
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 270
• Identity: 50/270 - (18%)
• Similarity: 89/270 - (32%)
• Gaps: 74/270 - (27%)

Human    92 SISTLNKRDYSLQIQNVDVTDD-GPYTCSVQT-QHTPRTMQ-----VHLTVQVPPKIYDISNDMT 149
            ||:|:..|       .||:.|| .....|::. :..||...     :..|...|.|:...
  Fly    19 SIATVRGR-------AVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQA----- 71

Human   150 VNEGTNVTLTCLATGKPEPSISW--RHI----------------SPSAKPFENGQYLDIYGITRD 196
              :|..:.:.|...|...|||.|  .|:                :|||.......::..:.::
  Fly    72 --DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLS-- 132

Human   197 QAGEYECSAEN---------------------DVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRS 240
            :|..|.|....                     :.::|..:|.:::......:..:.|....|
  Fly   133 EARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLP--- 194

Human   241 GLIRCEGAGVPPPAFEWYKGE-KKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 304
                |.....|.....|...| |::..|.:..::.|    ..|.::.:..|..|||.|:|.|.:|
  Fly   195 ----CRVHARPRAEITWLNNENKEIVQGHRHRVLAN----GDLLISEIKWEDMGNYKCIARNVVG 251

Human   305 TTNASLPLNP 314
            ...|...:.|
  Fly   252 KDTADTFVYP 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	11/49 (22%)
		IGc2	152..210	CDD:197706	14/96 (15%)
		Ig_3	225..301	CDD:372822	16/76 (21%)
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	17/74 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900