Protein Alignment NEGR1 and CG13506

DIOPT Version :10

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_611666.2
• Gene: CG13506 / 37556
• FlyBaseID: FBgn0034723
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 66/300 - (22%)
• Similarity: 119/300 - (39%)
• Gaps: 31/300 - (10%)

Human    41 PWAAVDNMMV--RKGDTAVLRCYLEDGASKGA--WLNRSSIIFAGGDKWSVDPRVSISTLNKRDY 101
            |:..|.::.|  :.||..:|.|...:.....|  |. ::.||.|.|.. .:..||.....|
  Fly    70 PYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVWY-KNRIIIANGQN-PISQRVQCMLNN---- 128

Human   102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISND-------MTVNEGTNVTLT 159
            |:.::||...|...|.|.:    .|:.::.|..::|..::..:.:|       .|..:|.:..|.
  Fly   129 SILLRNVSPEDSDDYYCEI----LPQRVRQHTALRVGARLSILCDDRDITDRSQTFRQGDHHKLE 189

Human   160 CLATGKPEPSISWR----HISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVV 220
            |........:|.|.    :..||:...:||..: :..:....||:|:|.|::....|....|.:.
  Fly   190 CRTYLPDNATIKWSFNDLNGQPSSVDNQNGVII-LDNVDEKNAGDYQCLADDGSRHPPHGTVHID 253

Human   221 VNFAPTIQEIKSGTVT-PGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGII---IQNFSTRSI 281
            |.::|.:...:....| .|.:..:.|.....|.....:.|..|.|....:..:   :.|...|:.
  Fly   254 VQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLSDKYSLKDSVHNDHNRTT 318

Human   282 LTVTNVTQEHFGNYTCVAANKLGTTNASLPLN-PPSTAQY 320
            |.|..||....|.|.|...|.:|:....:.:: .|.|.|:
  Fly   319 LIVREVTDSDLGEYLCQVENAIGSNEVKVHVSYNPETPQF 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG_like	47..135	CDD:214653	22/91 (24%)
		Ig strand B	56..60	CDD:409353	1/3 (33%)
		Ig strand C	68..72	CDD:409353	1/5 (20%)
		Ig strand E	101..105	CDD:409353	1/3 (33%)
		Ig strand F	115..120	CDD:409353	2/4 (50%)
		Ig strand G	128..131	CDD:409353	0/2 (0%)
		Ig_3	138..207	CDD:464046	16/79 (20%)
		IG_like	231..312	CDD:214653	18/84 (21%)
		Ig strand B	241..245	CDD:409353	0/3 (0%)
		Ig strand C	254..258	CDD:409353	0/3 (0%)
		Ig strand E	280..284	CDD:409353	1/3 (33%)
		Ig strand F	294..299	CDD:409353	2/4 (50%)
CG13506	NP_611666.2	Ig_3	69..146	CDD:464046	21/81 (26%)
		Ig_3	173..238	CDD:464046	14/65 (22%)
		Ig	258..349	CDD:472250	19/90 (21%)
		Ig strand B	275..279	CDD:409353	0/3 (0%)
		Ig strand C	288..292	CDD:409353	0/3 (0%)
		Ig strand E	317..321	CDD:409353	1/3 (33%)
		Ig strand F	331..336	CDD:409353	2/4 (50%)