Protein Alignment NEGR1 and DIP-iota

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001097100.1
• Gene: DIP-iota / 33925
• FlyBaseID: FBgn0031837
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 98/317 - (30%)
• Similarity: 144/317 - (45%)
• Gaps: 34/317 - (10%)

Human    16 WLAAVLLSLCCLLPSCLPAGQSVDFPWAA-VDNMMVRKGDTAVLRCYLEDGAS-KGAWL--NRSS 76
            ||  :||...|...:......:.|..::. ::|..|..|..|:|.|.:.|..| |.|||  :..:
  Fly     9 WL--LLLQSVCFSQASFSELNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFKVAWLRVDTQT 71

Human    77 IIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQV-HLTVQVPPK 140
            |:.......:.:.|:|||....|.:.|:|::|..:|.|.|.|.:.|.  |...|: :|.|.|||.
  Fly    72 ILSIQNHVITKNHRISISHTEHRIWQLKIRDVQESDRGWYMCQINTD--PMKSQMGYLDVVVPPD 134

Human   141 I--YDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPF------------ENGQYLDIY 191
            |  |..|.|:..:.|.||||||.|||.|.|:|:||.  ..|.|.            ..||.|.::
  Fly   135 IVDYQTSQDVVRSTGQNVTLTCSATGVPMPTITWRR--EEATPILISDDGDREVFSVEGQNLTLW 197

Human   192 GITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTI----QEIKSGTVTPGRSGLIRCEGAGVPP 252
            .:.|...|.|.|.|.|.|.....::|.:||||||||    ..|..|.   |:...:.|.....|.
  Fly   198 QVQRSHMGAYLCIASNGVPPTVSKRVMLVVNFAPTIWTRYDTIYVGL---GQKLTLECITESQPA 259

Human   253 PAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVT--NVTQEHFGNYTCVAANKLGTTN 307
            ....|.:..:.|..|....:..:...|.::.:|  .:|:..||.|.|.|.|.:|.|:
  Fly   260 SVNFWLRDSQLLQGGSYESVSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTD 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	29/91 (32%)
		IGc2	152..210	CDD:197706	26/69 (38%)
		Ig_3	225..301	CDD:372822	19/81 (23%)
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	28/87 (32%)
		Ig	39..122	CDD:299845	27/84 (32%)
		Ig	132..213	CDD:299845	31/82 (38%)
		IG_like	141..227	CDD:214653	30/87 (34%)
		IG_like	239..322	CDD:214653	19/81 (23%)
		IGc2	245..313	CDD:197706	15/67 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143459
Domainoid	1	1.000	59	1.000	Domainoid score	I10656
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8497
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.750