Protein Alignment NEGR1 and fipi

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_787975.1
• Gene: fipi / 33676
• FlyBaseID: FBgn0031627
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 339
• Identity: 80/339 - (23%)
• Similarity: 130/339 - (38%)
• Gaps: 81/339 - (23%)

Human    27 LLPSCLPAGQSVDFPWAAVDNMMVR--KGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDP 89
            |:..|......|:..|.:....::|  ||     |.::|..:::...:..:.|..|....||.:
  Fly    42 LIVQCRSPDPKVELHWKSPKGEIIREHKG-----RIHIEQTSTEQLKIVFAHIALADKGNWSCE- 100

Human    90 RVSISTLNKRDYSLQI-QNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEG 153
             .:..:|:.:.:.|.: |.:..|::.                   ||            |||.||
  Fly   101 -AADGSLHSKSFDLIVYQKITFTENA-------------------TV------------MTVKEG 133

Human   154 TNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLD-----------IYGITRDQAGEYECSA-- 205
            ...|:.|...|:|:|:::|..   :.:|...|...|           |..:|::..|||.|.|
  Fly   134 EKATILCEVKGEPQPNVTWHF---NGQPISAGAADDSKFRILADGLLINKVTQNDTGEYACRAYQ 195

Human   206 -ENDVSFPDVRKVKVVVNFAPTIQEIK---------SGTVTPGRSGLIRCEGAGVPPPAFEWYKG 260
             .:..|....|.|.:.:...|...:..         :||.|      :.||....||..|.||:.
  Fly   196 VNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYINGTAT------LMCEALAEPPANFTWYRK 254

Human   261 EKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPL----NPPSTAQYG 321
            ..||.:..:...||:.|..|.||:..:....|.||.|.|.|.|||...:..|    .|||.|.:.
  Fly   255 HNKLHSNNRLYTIQSDSYWSSLTIHVLNTSAFDNYRCRARNDLGTIERTTRLEQGEKPPSPANFQ 319

Human   322 ITG----SADVLFS 331
            :.|    :.||:.|
  Fly   320 LRGFNSNTFDVVLS 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	13/90 (14%)
		IGc2	152..210	CDD:197706	18/71 (25%)
		Ig_3	225..301	CDD:372822	24/84 (29%)
fipi	NP_787975.1	IG_like	33..115	CDD:214653	15/79 (19%)
		I-set	128..202	CDD:254352	21/76 (28%)
		Ig	133..>193	CDD:299845	16/62 (26%)
		IG_like	228..307	CDD:214653	27/84 (32%)
		Ig	235..305	CDD:143165	25/75 (33%)
		FN3	312..415	CDD:238020	8/22 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143446
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740