Protein Alignment NEGR1 and dpr3

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001014459.2
• Gene: dpr3 / 3346208
• FlyBaseID: FBgn0053516
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 309
• Identity: 63/309 - (20%)
• Similarity: 115/309 - (37%)
• Gaps: 91/309 - (29%)

Human    40 FPWAAVDNMMVRKGDT-AVLRCYLEDGASKG-AWLNRSS--IIFAGGDKWSVDPRVSIS-TLNKR 99
            |.:....|:..|.|.| |:::|.::....|. :|:.:..  |:..|...::.|.|..:: :.:.|
  Fly   238 FDFGMPRNITGRTGHTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSR 302

Human   100 DYSLQIQNVDVTDDGPYTCSVQTQHTPR---TMQVHLTVQVPPKIYDISN---DMTVNEGTNVTL 158
            :::|.::.....|.|.|.|.|.|:  |:   ..|::: :::.|....:.:   |:....|:.:.|
  Fly   303 EWTLHVKAPLAKDSGIYECQVNTE--PKMSMAFQLNI-IEISPDAKAVISGPPDLHFKAGSAIIL 364

Human   159 TCLATGKPEPSIS------WRHISPSAKPF--ENGQYLDIYGITRDQAGEYECSAENDVSFPDVR 215
            .||.   .:||:.      |........||  ::||.....|......|..|.::.||:    :.
  Fly   365 NCLV---QQPSVKDIGPIYWYRGEHMITPFDADDGQPEIPAGRGEHPQGIPEDTSPNDI----MS 422

Human   216 KVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRS 280
            :|.:.:.||..|                          |.|...|:               :.:|
  Fly   423 EVDLQMEFATRI--------------------------AMESQLGD---------------TLKS 446

Human   281 ILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSADVL 329
            .|.::|......|||||                .|:||     .||.||
  Fly   447 RLRISNAQTTDTGNYTC----------------QPTTA-----SSASVL 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	22/95 (23%)
		IGc2	152..210	CDD:197706	16/65 (25%)
		Ig_3	225..301	CDD:372822	12/75 (16%)
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	21/88 (24%)
		IG_like	243..329	CDD:214653	21/87 (24%)
		Ig	350..464	CDD:299845	32/177 (18%)
		IG_like	<441..477	CDD:214653	16/70 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810