DRSC/TRiP Functional Genomics Resources

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Protein Alignment NEGR1 and dpr18

DIOPT Version :9

Sequence 1:NP_776169.2 Gene:NEGR1 / 257194 HGNCID:17302 Length:354 Species:Homo sapiens
Sequence 2:NP_573102.1 Gene:dpr18 / 32572 FlyBaseID:FBgn0030723 Length:519 Species:Drosophila melanogaster


Alignment Length:325 Identity:73/325 - (22%)
Similarity:121/325 - (37%) Gaps:67/325 - (20%)


- Green bases have known domain annotations that are detailed below.


Human    46 DNMM--VRKGDTAVLRC---YLEDGASKGAWLNRS----SIIFAGGDKWSVDPRVSISTLNKRDY 101
            ||::  |.....|||.|   .|:|  ....|:.|:    |::..|...:|.|||:.:......::
  Fly   230 DNLVSAVHLFTEAVLNCRVGMLKD--KTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNW 292

Human   102 SLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPP-KIYDIS----NDMTVNEGTNVTLTCL 161
            .|.|......|.|.|.|.|.| |.||....:|||..|| :|.|..    .|.....|:.|.|.| 
  Fly   293 RLLINPTQTEDAGVYMCQVST-HPPRVFTTNLTVLEPPLRIIDEHERDVGDRYYKSGSTVDLQC- 355

Human   162 ATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPT 226
                        .||.|....|....|.    :.|.|.:......|:.:    .::.::.|...|
  Fly   356 ------------QISRSFFQKERQTILK----STDSANDAVQKLINETT----SELNLIGNVNQT 400

Human   227 IQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSI-----LTVTN 286
            ..:.....:....:..|            .|.|.|:.|    ||:..:..|...:     :::.:
  Fly   401 QHKFSGQDLEKYFTKFI------------TWAKDEEPL----QGMTNRRLSVSDVWLTSRISIGD 449

Human   287 VTQEHFGNYTCVAANKLGTTNASLPL---NPPSTAQYGITGSADVLFS---CWYLVLTLSSFTSI 345
            ......|||:| :..:|.|....:.:   ..|:..|:.| ||...::|   ..:|::.:..||.:
  Fly   450 AKLSDSGNYSC-SLGRLFTVIVQVQVLTGELPAAVQHNI-GSRTEIYSLAMLGHLLVLIFLFTCL 512

Human   346  345
              Fly   513  512

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NEGR1NP_776169.2 IG 47..135 CDD:214652 28/96 (29%)
IGc2 152..210 CDD:197706 12/57 (21%)
Ig_3 225..301 CDD:372822 13/80 (16%)
dpr18NP_573102.1 IG_like 242..325 CDD:214653 26/85 (31%)
Ig <258..326 CDD:299845 21/68 (31%)
IGc2 <417..461 CDD:197706 12/60 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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