Protein Alignment NEGR1 and dpr7

DIOPT Version :10

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001096850.2
• Gene: dpr7 / 2768865
• FlyBaseID: FBgn0053481
• Length: 312
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 62/338 - (18%)
• Similarity: 109/338 - (32%)
• Gaps: 128/338 - (37%)

Human    43 AAVDNMMVRKGDTAVLRCYLED-GASKGAWLNRSSI--------IFAGGDKWSVDPRVSISTLNK 98
            |.||       :.|:|||.::: |....:|:.:..:        .:.|..::||     |.....
  Fly    63 AVVD-------EIAILRCRVKNKGNRTVSWMRKRDLHILTTNIYTYTGDQRFSV-----IHPPGS 115

Human    99 RDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLAT 163
            .|:.|:|......|.|.|.|.|.|:               |||             |:.: ||
  Fly   116 EDWDLKIDYAQPRDSGVYECQVNTE---------------PKI-------------NLAI-CL-- 149

Human   164 GKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVS-------FPDVRKVKVVV 221
                                                  :..|:||..       |.|.:..:..:
  Fly   150 --------------------------------------QVIADNDFQDLKTKKRFYDTKSARAKI 176

Human   222 NFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKL-FNGQQGIII-----QNFSTRS 280
            ..:..|...:..|:.      :.| ...:..|:..||.|...: |:..:|.|.     .:..|.|
  Fly   177 LGSTEIHVKRDSTIA------LAC-SVNIHAPSVIWYHGSSVVDFDSLRGGISLETEKTDVGTTS 234

Human   281 ILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG--------SADVLFSCWYLVL 337
            .|.:|..:....||||||       .|.::   |.|...:.:||        |:.:....:..::
  Fly   235 RLMLTRASLRDSGNYTCV-------PNGAI---PASVRVHVLTGEQPAAMQTSSAIRIRAFTAMI 289

Human   338 TLSSFTSIFYLKN 350
            |:.|...:.|:.:
  Fly   290 TIISTKVLLYISS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG_like	47..135	CDD:214653	19/96 (20%)
		Ig strand B	56..60	CDD:409353	2/3 (67%)
		Ig strand C	68..72	CDD:409353	0/3 (0%)
		Ig strand E	101..105	CDD:409353	1/3 (33%)
		Ig strand F	115..120	CDD:409353	2/4 (50%)
		Ig strand G	128..131	CDD:409353	0/2 (0%)
		Ig_3	138..207	CDD:464046	7/68 (10%)
		IG_like	231..312	CDD:214653	20/86 (23%)
		Ig strand B	241..245	CDD:409353	0/3 (0%)
		Ig strand C	254..258	CDD:409353	0/3 (0%)
		Ig strand E	280..284	CDD:409353	2/3 (67%)
		Ig strand F	294..299	CDD:409353	4/4 (100%)
dpr7	NP_001096850.2	V-set	56..145	CDD:462230	25/121 (21%)
		Ig	184..267	CDD:472250	22/99 (22%)
		Ig strand B	190..194	CDD:409353	0/9 (0%)
		Ig strand C	202..206	CDD:409353	0/3 (0%)
		Ig strand E	234..238	CDD:409353	2/3 (67%)
		Ig strand G	261..264	CDD:409353	0/2 (0%)