Protein Alignment NEGR1 and rig-5

DIOPT Version :9

• Sequence 1: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001251131.1
• Gene: rig-5 / 172791
• WormBaseID: WBGene00004372
• Length: 482
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 87/308 - (28%)
• Similarity: 130/308 - (42%)
• Gaps: 54/308 - (17%)

Human    35 GQSVDFPWAAVDNMMVRKGDTAVLRCYLED-GASKGAWLNRSS---------IIFAGGDKWSVDP 89
            ||.|||                  .|.:.| |:...|::...|         .:|...:|:.:.|
 Worm    99 GQDVDF------------------TCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRNKYELKP 145

Human    90 RVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQV-HLTVQVPPKI-YDISNDMTVNE 152
            |  |..|: .::.|.|:||..:|.|.|:|.:.|:  |.|:.. .|.|:|||.: ......:.|.|
 Worm   146 R--IGDLH-NEWVLTIKNVQESDRGNYSCQINTE--PITLSTGELDVKVPPVVSRSTPAAVEVRE 205

Human   153 GTNVTLTCLATGKPEPSISWRH-----------ISPSAKPFENGQYLDIYGITRDQAGEYECSAE 206
            |.||:|||.|.|.|.|::.||.           ....|..| :|..|.:..::|....||.|.|.
 Worm   206 GNNVSLTCKADGNPTPTVIWRRQDRQIIRYNGATGFGASVF-HGPVLHLTKVSRKHMSEYLCVAS 269

Human   207 NDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIR--CEGAGVPPPAFEWYKGEKKLFNGQQ 269
            |.:...:...||::|.|.|.:| .:|.||......:.|  |.....|.|...|.|..:.::....
 Worm   270 NGIPPDESWTVKLLVTFPPLVQ-AQSETVQASVGSMARMVCTTEAWPRPEMGWEKDGEPVYESNN 333

Human   270 GIIIQNFSTR----SILTVTNVTQEHFGNYTCVAANKLGTTNASLPLN 313
            ..:....|.:    .||.:.||...|||.|.|||.|..|..::.:.||
 Worm   334 VAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTLN 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NEGR1	NP_776169.2	IG	47..135	CDD:214652	23/98 (23%)
		IGc2	152..210	CDD:197706	23/68 (34%)
		Ig_3	225..301	CDD:372822	23/81 (28%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	29/112 (26%)
		Ig_3	191..270	CDD:372822	24/79 (30%)
		IG	294..380	CDD:214652	23/85 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C161450903
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	114	1.000	Inparanoid score	I3823
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm15630
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.900