DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Has2 and kkv

DIOPT Version :9

Sequence 1:	NP_037285.1	Gene:	Has2 / 25694	RGDID:	2781	Length:	552	Species:	Rattus norvegicus
Sequence 2:	NP_524233.1	Gene:	kkv / 45884	FlyBaseID:	FBgn0001311	Length:	1615	Species:	Drosophila melanogaster

Alignment Length:	539	Identity:	104/539 - (19%)
Similarity:	178/539 - (33%)	Gaps:	195/539 - (36%)

- Green bases have known domain annotations that are detailed below.

  Rat    40 DNYYFSFGLYGAFLASHLIIQSLFAFLEHRKMKKSLETPIKLNKTVALCIAAYQEDPDYLRKCLQ 104
            |..|:.|       .:|:.....|...:|.      :..|:.|:.|.|.||...|....:.   |
  Fly   622 DPDYYEF-------ETHIFFDDAFEISDHS------DDDIQCNRFVKLLIATMDEAASEIH---Q 670

  Rat   105 SVKRL----TYP---GIKVVMVIDGNSDDDLYMMDIFSEVMGRDKSVTYIWKNNFHERGPGETEE 162
            :..||    .||   |.::|..:.                 |:.|.:|::
  Fly   671 TTIRLRPPKKYPTPYGGRLVWTLP-----------------GKTKFITHL--------------- 703

  Rat   163 SHKESSQHVTQLVLSNKSICIMQKWGGKREVMYTAFRALGR-------SVD---------YVQVC 211
            ..|:..:|             .::|.   :||| .:..||.       |||         |:...
  Fly   704 KDKDRIRH-------------RKRWS---QVMY-MYYLLGHRLMELPISVDRKDAIAENTYLLTL 751

  Rat   212 DSDTMLDPASSVEMVKVLEEDPMVGGVGGDVQILNKYDS-WIS-FLSSVRYWMAFNIERACQSYF 274
            |.|....|.:...:|.:::::..:|...|.:..:..... |.. |..::.:|    :::|.:...
  Fly   752 DGDIDFKPNAVTLLVDLMKKNKNLGAACGRIHPVGSGPMVWYQLFEYAIGHW----LQKATEHMI 812

  Rat   275 GCVQCISGPLGMYRNSLL----------------HEFVEDWYNQEFMGNQCSFGDDRHLTNRVLS 323
            |||.|..|...::|...|                ..:|:  |:|         |:||.|...:|.
  Fly   813 GCVLCSPGCFSLFRGKALMDDNVMKKYTTRSDEARHYVQ--YDQ---------GEDRWLCTLLLQ 866

  Rat   324 LGYATKYTARSKCLTETPIEYLRWLNQQTRWSKS---YFREWLYNAMWFHKHH-----LWMTYEA 380
            .||..:|:|.|...|..|..:..:.||:.||..|   ...:.|.:|....|.:     |::.|:.
  Fly   867 RGYRVEYSAASDAYTHCPEGFNEFYNQRRRWVPSTIANIMDLLADAKRTIKINDNISLLYIFYQM 931

  Rat   381 VITG---FFP---FFLIATVIQLFYRGKIW----------------------NILLFLLTVQ--- 414
            ::.|   ..|   |.::.......:|...|                      ||.||:..|.
  Fly   932 MLMGGTILGPGTIFLMLVGAFVAAFRIDNWTSFHYNIVPILAFMFICFTCKSNIQLFVAQVLSTA 996

  Rat   415 ----------------------------LVGLIKSSF-ASCLRGN----IVMVFMSLYSVLYMSS 446
                                        |:.::.|.| |:||...    |....:.|.|:..|..
  Fly   997 YALIMMAVIVGTALQLGEDGIGSPSAIFLISMVGSFFIAACLHPQEFWCITCGLIYLLSIPSMYL 1061

  Rat   447 LLPAKMFAIATINKAGWGT 465
            ||  .:::|..:|...|||
  Fly  1062 LL--ILYSIINLNVVSWGT 1078

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Has2	NP_037285.1	nodulat_NodC	48..463	CDD:275076	98/527 (19%)
Has2	NP_037285.1	GT2_HAS	84..361	CDD:133056	64/320 (20%)
kkv	NP_524233.1	Chitin_synth_C	583..904	CDD:133033	72/361 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	53	1.000	Domainoid score	I11041
eggNOG	1	0.900	-	-		E1_COG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770