DRSC/TRiP Functional Genomics Resources

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Protein Alignment Il1r1 and Dscam2

DIOPT Version :9

Sequence 1:NP_037255.3 Gene:Il1r1 / 25663 RGDID:2892 Length:590 Species:Rattus norvegicus
Sequence 2:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster


Alignment Length:647 Identity:129/647 - (19%)
Similarity:215/647 - (33%) Gaps:187/647 - (28%)


- Green bases have known domain annotations that are detailed below.


  Rat    27 LIVPLLSLE--------TDKCT----------------------EYPNEVISFSSVNEIDIRSCP 61
            |:.|:|::|        ..|||                      |....|:|.......:.| |.
  Fly   290 LLGPILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNVLSVHMGGTAEFR-CL 353

  Rat    62 LTPNEMHGG--TIIWYKNDSKTPISADKDSRIHQQNEHLWFVP-AKMEDSGYYYCIMR---NSTY 120
            :|.|....|  .|:|||:..:.|.|    .|:    |....|| ...|:.|.|.|::|   ..|:
  Fly   354 VTSNGSPVGMQNILWYKDGRQLPSS----GRV----EDTLVVPRVSRENRGMYQCVVRRPEGDTF 410

  Rat   121 CLKTKITMSVLENDPGLCYNTQASFIQRLHVAGDG-SLVCPYLDFFKDENNELPKVQWYKNCKPL 184
            ....::.:.  :..|.|.|    |||::....|.. ||.|      ....|..|::.|..:..||
  Fly   411 QATAELQLG--DAPPVLLY----SFIEQTLQPGPAVSLKC------SAAGNPTPQISWTLDGFPL 463

  Rat   185 PLDDGNFF---------GFKNKLMVMNVAEEHRGNYTC-------RTSYTYQGKQY--PVTRVIT 231
            | .:|.|.         ...:.:.:.:|..|..|.|.|       |..:..:...|  |..|:|.
  Fly   464 P-SNGRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIRLIP 527

  Rat   232 FITIDDSKRDRPVIMSPRNETMEADPGSTIQLICNVTGQFTDLVYWKWNGSEIEWDDPILAEDYQ 296
            .:|                    |..|.|:.|.|.|.|...:.::|:..|.|       |.:|.:
  Fly   528 KVT--------------------AVSGETLNLKCPVAGYPIEEIHWERGGRE-------LPDDIR 565

  Rat   297 FLEHPSAKRKYTLITTLNVSEVKSQFYRYPFICFVKNTH---ILETAHVRLVYP---VPDFKNYL 355
            ....|..        :|.:|.|:.......:.|:.:|..   ...:..|.::.|   .|...|.|
  Fly   566 QRVQPDG--------SLTISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVIVPPKLSPFQTNIL 622

  Rat   356 ---IGGFAIFTATAVFCACIYKVFKVDIVL---WYRDSCSDFLPPKASDGKTYDAY--VLYPKTY 412
               :|..|..|.:.|         |.|:.|   |.:|. ....|.:....|..|.|  :|..:..
  Fly   623 QLNMGDRASLTCSVV---------KGDLPLTINWRKDG-RPIDPTQHMSVKQVDQYNSILVIENL 677

  Rat   413 GEGSFAYLDTFVFKLLPEVLEGQFGYKLFICGRDDYVGEDTIEVTNENVKRSRRLI--------- 468
            |..........|.....||...|   .|.:.....::    :|..:.||:|:|.::         
  Fly   678 GSDHTGNYSCVVRNSAAEVENSQ---ALLVNVPPRWI----VEPVDANVERNRHIMLHCQAQGVP 735

  Rat   469 ---IILVRDMGSFS-------------CLGQSS-------EEQIAIYDALIREGI-----KIILL 505
               |:..:..||.|             .||..|       |::...|......||     |:|.|
  Fly   736 TPSIVWKKATGSKSGEYEEVRERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQL 800

  Rat   506 ELEKIQDYEKMPESIQFIKQKHGAICWSGDFKERP------QSAKTRFWKNLRYQMPAQRRS 561
            ::.....:.....|: .:|:...|:.......::|      :|.|.....:..|::..::.:
  Fly   801 KVNSSPYFSSTSRSV-MVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEA 861

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Il1r1NP_037255.3 Ig 47..130 CDD:299845 22/88 (25%)
Ig2_IL1R_like 144..236 CDD:143234 26/110 (24%)
Ig_3 242..333 CDD:290638 17/90 (19%)
IG_like 251..344 CDD:214653 19/95 (20%)
TIR 401..556 CDD:214587 35/199 (18%)
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352 7/36 (19%)
Ig 247..327 CDD:299845 7/36 (19%)
I-set 332..418 CDD:254352 24/94 (26%)
IGc2 344..407 CDD:197706 20/71 (28%)
IG_like 432..517 CDD:214653 18/91 (20%)
IGc2 436..507 CDD:197706 17/77 (22%)
I-set 521..610 CDD:254352 23/123 (19%)
IGc2 533..597 CDD:197706 17/78 (22%)
Ig 630..699 CDD:143165 17/78 (22%)
IG_like 714..802 CDD:214653 18/87 (21%)
Ig 725..802 CDD:299845 14/76 (18%)
Ig 823..894 CDD:143165 5/39 (13%)
FN3 906..1006 CDD:238020
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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