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Protein Alignment MFSD8 and ATR1

DIOPT Version :10

Sequence 1:	NP_001358520.1	Gene:	MFSD8 / 256471	HGNCID:	28486	Length:	521	Species:	Homo sapiens
Sequence 2:	NP_013591.1	Gene:	ATR1 / 854924	SGDID:	S000004584	Length:	542	Species:	Saccharomyces cerevisiae

Alignment Length:	404	Identity:	68/404 - (16%)
Similarity:	140/404 - (34%)	Gaps:	118/404 - (29%)

- Green bases have known domain annotations that are detailed below.

Human     7 ESEQEPLLGDTPGSREWDILETEEHYKSRWRSIRILY---LTMFLSSVGFSVVMMSIWPYLQKID 68
            :||.|.:    ..:::|   :...::|..|:....::   ::..|:..| :...:||...|....
Yeast    44 QSEDEMV----DSNQKW---QNPNYFKYAWQEYLFIFTCMISQLLNQAG-TTQTLSIMNILSDSF 100

Human    69 PTADTSFLGWVIASYSL--GQMV-----ASPIFGLWSNYRPRKEPLIVSILISVAANCLYAYLHI 126
            .:...| ..|::||:.|  |..:     ...|:||       |:.|:|..::.:..:.:......
Yeast   101 GSEGNS-KSWLMASFPLVSGSFILISGRLGDIYGL-------KKMLLVGYVLVIIWSLICGITKY 157

Human   127 PASHNKYYMLVARGLLGIGAGNV-----AVVRSYTAGATSLQERTSSMANISMCQALGFILGPVF 186
            ..|..  :.:::|...|:|...|     .::.:...|.|..:....|.  :.....:|..||.:|
Yeast   158 SGSDT--FFIISRAFQGLGIAFVLPNVLGIIGNIYVGGTFRKNIVISF--VGAMAPIGATLGCLF 218

Human   187 QTCFTFLGEKGVTW--------DVIKLQINMYTTPVL------------LSAFLGILNIILILAI 231
            .........|...|        ..|...:::|..|..            :.:.||::.:||:..:
Yeast   219 AGLIGTEDPKQWPWAFYAYSIAAFINFVLSIYAIPSTIPTNIHHFSMDWIGSVLGVIGLILLNFV 283

Human   232 LREHRVDDSGRQCKSINFEEASTDEAQVPQGNIDQVAVVAINVLFFVTLFIFALFETII--TPLT 294
            ..                        |.|....:|..::.|.::..:.|.:|.::|...  |||.
Yeast   284 WN------------------------QAPISGWNQAYIIVILIISVIFLVVFIIYEIRFAKTPLL 324

Human   295 MDMYAWTQEQAVLYN----GIILA------ALGVEAVVIF---LGVKLLSKKIGERAILLGGLIV 346
                    .:||:.:    .|:||      :.|:.....|   |.::..:              .
Yeast   325 --------PRAVIKDRHMIQIMLALFFGWGSFGIFTFYYFQFQLNIRQYT--------------A 367

Human   347 VWVG--FFILLPWG 358
            :|.|  :|:.|.||
Yeast   368 LWAGGTYFMFLIWG 381

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.