Protein Alignment Cyp3a23-3a1 and Cyp6a19

DIOPT Version :9

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_611001.2
• Gene: Cyp6a19 / 36662
• FlyBaseID: FBgn0033979
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 522
• Identity: 153/522 - (29%)
• Similarity: 253/522 - (48%)
• Gaps: 85/522 - (16%)

  Rat     3 LLSALTLETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKP-------------LPFFGTVLNYY 54
            ::..|||..|.:|            :.:..:|::|||...|             :|..|.:...|
  Fly     8 VVGVLTLVAWWVL------------QNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGILKRTY 60

  Rat    55 MGLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECF------SVFTNRRDFGPVGI 113
            :   ||..:..   |...|.:...|....|||.:.:|.||::: |      .|:.|.:| .|
  Fly    61 L---KFRKQTD---GPFAGFYLYAMKYIVITDVDFVKTVLIRD-FDKFHDRGVYHNEKD-DP--- 114

  Rat   114 MGKAISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQE---KGKPVPVKEVFG 175
            :...::..:.::||..|..|:.||||.::|.||..:...||.:::.:.::   ..:.:.|.::..
  Fly   115 LTNNLATIEGQKWKNLRQKLTHTFTSAKMKSMFSTVLNVGDEMIRVVDEKISSSSQTLEVTDIVS 179

  Rat   176 AYSMDVITSTSFGVNVDSLNNPKDPFVEKAKKLLR-------ID--FFDPLFLSVVL-FPFLTPV 230
            .::.|||...:||:..:||.:||..||:.....||       :|  .|....|:|.| |.||.|.
  Fly   180 RFTSDVIGICAFGLKCNSLRDPKAEFVQMGYSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPS 244

  Rat   231 YEMLNICMFPKDSIEFFKKFV-----YRMKETRLDSVQKHRVDFLQLM--MNAHNDSKDKESHTA 288
            .:            :|:.|.|     ||||.      :..|.||:..:  |....|..|||:..|
  Fly   245 VQ------------KFYMKIVQDTIDYRMKR------KVTRNDFMDTLIDMKQQYDKGDKENGLA 291

  Rat   289 LSDMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPN-KAPPTYDTVMEM 352
            .:  |:.||:.:|..||:|..|:|:.|.|:.||.:.|.|.||:.|||..|.. .....||::.::
  Fly   292 FN--EVAAQAFVFFLAGFEAGSTTMGFTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDL 354

  Rat   353 EYLDMVLNETLRLYPIGNRLERVCKKDVEING--VFMPKGSVVMIPSYALHRDPQHWPEPEEFRP 415
            .|::.|:||:||.:|:...|.|:..|..:.:.  .|:..|:.|::.:..:|.||:.:||||:|.|
  Fly   355 FYMEKVINESLRKHPVVAHLARIATKPYQHSNPKYFIEAGTGVLVSTLGIHHDPEFYPEPEKFIP 419

  Rat   416 ERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQG 480
            |||.:|.........:||||.|||||||:||..|.:.:.|..::.||.|:...:|.:|:|.:...
  Fly   420 ERFDEEQVKKRPTCAFLPFGAGPRNCIGLRFGRMQVIIGLALLIHNFRFELHPKTPVPMKYTINN 484

  Rat   481 LL 482
            ||
  Fly   485 LL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	145/486 (30%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	145/486 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870