Protein Alignment Cyp3a23-3a1 and Cyp6a13

DIOPT Version :9

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_610390.1
• Gene: Cyp6a13 / 35837
• FlyBaseID: FBgn0033304
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 500
• Identity: 170/500 - (34%)
• Similarity: 272/500 - (54%)
• Gaps: 41/500 - (8%)

  Rat     7 LTLETWVLLAVVLVLLYGFGTRTH-GLFKKQGIPGPKPLPFFGTVLNYYMGL-W-KFDVECHKKY 68
            |||  .||:..|.:||| ...|.| ..:.::|:.|.:|:.|.|.:......| | ..::..::|:
  Fly     2 LTL--LVLVFTVGLLLY-VKLRWHYSYWSRRGVAGERPVYFRGNMSGLGRDLHWTDINLRIYRKF 63

  Rat    69 ---GKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPV---GIMGKAISVSKDEEWK 127
               .:..|.|........|.|.|:|::::::: ||.|.:|..|..|   .:.|..:.:. ..||:
  Fly    64 RGVERYCGYFTFMTKSLFIMDLELIRDIMIRD-FSSFADRGLFHNVRDDPLTGNLLFLD-GPEWR 126

  Rat   128 RYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEKGKPVPVKEVFGAYSMDVITSTSFGVNVD 192
            ..|..|:..||||::|.|||.:.:.|:.|.:..|.:.|: :..|::...::.|||.|.:||:..:
  Fly   127 WLRQNLTQVFTSGKMKFMFPNMVEVGEKLTQACRLQVGE-IEAKDLCARFTTDVIGSCAFGLECN 190

  Rat   193 SLNNPKDPFVEKAKKLLRIDFFDPLF-LSVVLFPFLTP-VYEMLNICMFPKDSIEFFKKFV---- 251
            ||.:|:..|....:.:.:    :||. :.|..|.|..| :...|...:|..:..|||...|
  Fly   191 SLQDPESQFRRMGRSVTQ----EPLHSVLVQAFMFAQPELARKLRFRLFRPEVSEFFLDTVRQTL 251

  Rat   252 -YRMKETRLDSVQKHRVDFLQLMMNAHNDS-KDKESHTALSDMEITAQSIIFIFAGYEPTSSTLS 314
             ||.:|      ..||.|.:||:|....:. ||     |||..:|.||:::|..||::.:|:|:|
  Fly   252 DYRRRE------NIHRNDLIQLLMELGEEGVKD-----ALSFEQIAAQALVFFLAGFDTSSTTMS 305

  Rat   315 FVLHSLATHPDTQKKLQEEIDRALP-NKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCKK 378
            |.|:.||.:||.|::|:.|:...|. |....|||:|.||.|||.|:.||||.|||...|.|...|
  Fly   306 FCLYELALNPDVQERLRVEVLAVLKRNNQKLTYDSVQEMPYLDQVVAETLRKYPILPHLLRRSTK 370

  Rat   379 DVEI--NGVFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGNGPRNC 441
            :.:|  :.:.:..||.::||.:::|.||:.:|:||:|.|.||..|...:..|:.|||||.|||||
  Fly   371 EYQIPNSNLILEPGSKIIIPVHSIHHDPELYPDPEKFDPSRFEPEEIKARHPFAYLPFGEGPRNC 435

  Rat   442 IGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGLLQPTK 486
            ||.||..:.:|:.|..:|::|.|...::||||||.|.:..|..|:
  Fly   436 IGERFGKLQVKVGLVYLLRDFKFSRSEKTQIPLKFSSRNFLISTQ 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	158/466 (34%)
Cyp6a13	NP_610390.1	p450	33..476	CDD:278495	156/460 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870