Protein Alignment Cyp3a23-3a1 and Cyp6a14

DIOPT Version :9

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_001286199.1
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 179/531 - (33%)
• Similarity: 268/531 - (50%)
• Gaps: 73/531 - (13%)

  Rat     9 LETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKFDVECHKKY----- 68
            |.|..|:.|||.|.|....:....:|::|:|...|||..|.:....           |||
  Fly     2 LFTIALVGVVLGLAYSLHIKIFSYWKRKGVPHETPLPIVGNMRGIV-----------KKYHFRDI 55

  Rat    69 -GKIWGLFDGQMPLFA----------ITDTEMIKNVLVKECFS------VFTNRRDFGPVGIMGK 116
             .:|:..|.||.|:..          |||.:.||.|::|: ||      .|||.||....|
  Fly    56 NQRIYKKFKGQGPIAGMYMFFKRTALITDLDFIKQVMIKD-FSYFQDRGAFTNPRDDPLTG---- 115

  Rat   117 AISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYG-------DILVKYLRQEKGKPVPVKEVF 174
            .:...:.|||:..|..|:|.||||::|:|..||...|       |..||..:.|:|. |.:|::.
  Fly   116 HLFALEGEEWRAMRHKLTPVFTSGKIKQMSKVIVDVGLRLGDAMDKAVKEAKVEEGN-VEIKDLC 179

  Rat   175 GAYSMDVITSTSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVVLFPFL---TPVYEMLNI 236
            ..::.|||.|.:||:..:||.:|...|.:|.:::     |.....|.::..|:   ..:...|.|
  Fly   180 ARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREI-----FTRRRHSTLVQSFIFTNARLARKLRI 239

  Rat   237 CMFPKDSIEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKE----------SHTALSD 291
            .:.|.|..:||...|....:.||.:..| |.||::.|:...  ::|:|          || .|:.
  Fly   240 KVLPDDLTQFFMSTVKNTVDYRLKNGIK-RNDFIEQMIELR--AEDQEAAKKGQGIDLSH-GLTL 300

  Rat   292 MEITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPN--KAPPTYDTVMEMEY 354
            .::.||:.:|..||:|.:|||:|..|:.||..||.|::|:|||:..|.|  .....||.:.:|.|
  Fly   301 EQMAAQAFVFFVAGFETSSSTMSLCLYELALQPDIQQRLREEIESVLANVDGGELNYDVLAQMTY 365

  Rat   355 LDMVLNETLRLYPIGNRLERVCKKDVEI--NGVFMPKGSVVMIPSYALHRDPQHWPEPEEFRPER 417
            ||.||:||||.:|:...|.|...||.:|  :.:.:.||.:.:||.:.:|.||:.:||||:|.|.|
  Fly   366 LDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIVLDKGILALIPVHNIHHDPEIYPEPEKFDPSR 430

  Rat   418 FSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGLL 482
            |..|...:..|..|||||:|||||||:||..:..|:.|..:|:.|.|.....|.:||..|::..|
  Fly   431 FDPEEVKNRHPMAYLPFGDGPRNCIGLRFGKIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKKSFL 495

  Rat   483 QPTKP-IILKV 492
            ..|.. |.|||
  Fly   496 LTTNDGIYLKV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	167/499 (33%)
Cyp6a14	NP_001286199.1	p450	32..506	CDD:306555	167/499 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870