Protein Alignment Cyp3a23-3a1 and Cyp9b1

DIOPT Version :9

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_523645.1
• Gene: Cyp9b1 / 35634
• FlyBaseID: FBgn0015038
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 515
• Identity: 157/515 - (30%)
• Similarity: 264/515 - (51%)
• Gaps: 42/515 - (8%)

  Rat     9 LETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKFDVECHKKYG---- 69
            :|..::||.:.:||:.:.|.|...|:.:.:...||.||.|.:....:....|..:..:.|.
  Fly     4 VEICLVLATIGLLLFKWSTGTFKAFEGRNLYFEKPYPFLGNMAASALQKASFQKQISEFYNRTRH 68

  Rat    70 -KIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVG--IMGKAISVSKDEEWKRYRA 131
             |:.|||:.:.|:..|.|.::||.:.||: |..|.|.:......  ::...::|.:|:.|:..|:
  Fly    69 HKLVGLFNLRTPMIQINDPQLIKKICVKD-FDHFPNHQTLNIPNERLVNDMLNVMRDQHWRNMRS 132

  Rat   132 LLSPTFTSGRLKEMFPVIEQYGDILVKYLRQ-------EKGKPVPVKEVFGAYSMDVITSTSFGV 189
            :|:|.|||.:::.||.::.:.....:::|:.       |....:.:|.:....|.|||.:|:||:
  Fly   133 VLTPVFTSAKMRNMFTLMNESFAQCLEHLKSSQPIAAGENAFELDMKVLCNKLSNDVIATTAFGL 197

  Rat   190 NVDSLNNPKDPFVEKAKKLLRIDFFDPL-FLSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVYR 253
            .|:|.::|::.|....|.|.   |...| ||..::......|:....:.:|...::|:|.:.|..
  Fly   198 KVNSFDDPENEFHTIGKTLA---FSRGLPFLKFMMCLLAPKVFNFFKLTIFDSTNVEYFVRLVVD 259

  Rat   254 MKETRLDSVQKH---RVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLSF 315
            ..:.|    :||   |.|.:||:|.|..:|||.     .:|.||.||..||.||.:|..|:.:..
  Fly   260 AMQYR----EKHNITRPDMIQLLMEAKKESKDN-----WTDDEIVAQCFIFFFAAFENNSNLICT 315

  Rat   316 VLHSLATHPDTQKKLQEEI---DRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCK 377
            ..:.|..:.|.|::|.||:   ..||.. ||.|||...||.|:|||::|:||.:.:....:|:|.
  Fly   316 TAYELLRNLDIQERLYEEVKETQEALKG-APLTYDAAQEMTYMDMVISESLRKWTLSAAADRLCA 379

  Rat   378 KDVEING-----VFMPK-GSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYLPFGN 436
            ||..:..     :|..| |..:.||...||.|.:.:|:|:.|.|||||:..|..:.||.|||||.
  Fly   380 KDYTLTDDEGTKLFEFKAGDNINIPICGLHWDERFFPQPQRFDPERFSERRKKDLIPYTYLPFGV 444

  Rat   437 GPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGL-LQPTKPIILKVVPR 495
            |||:|||.|:|:|..|..|..::.|:..:....|...:..|.:|. :.||....:::|.|
  Fly   445 GPRSCIGNRYAVMQAKGMLYNLMLNYKIEASPRTTRDMWESARGFNIIPTTGFWMQLVSR 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	147/480 (31%)
Cyp9b1	NP_523645.1	p450	37..478	CDD:299894	142/454 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H133568
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm9060
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870