Protein Alignment Cyp3a23-3a1 and Cyp28c1

DIOPT Version :10

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_572752.1
• Gene: Cyp28c1 / 32138
• FlyBaseID: FBgn0030339
• Length: 505
• Species: Drosophila melanogaster
• Alignment Length: 528
• Identity: 132/528 - (25%)
• Similarity: 232/528 - (43%)
• Gaps: 74/528 - (14%)

  Rat    15 LAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWKF-----DVECHKKYGKIW-G 73
            :|.:|..:|.|.....|.::::|:..|:.||.||:..|.......|     |:..|.:....: |
  Fly     9 IATLLGAIYAFLVSNFGHWRRRGVTEPRALPLFGSFPNMIWPRQHFTMDMRDIYMHYRNTHSYVG 73

  Rat    74 LFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAISVSKD------------EEW 126
            .:..:.|...:.:..::..:.| ..||.|.|..       ..|.:.::||            |||
  Fly    74 CYLLRAPKLLVLEPRLVYEIYV-SAFSHFENND-------ASKMVDIAKDRLVALNPFVLEGEEW 130

  Rat   127 KRYRALLSPTFTSGRLKEMFPVIEQYGDILVKY--LRQEKGKPVPVKEVFGAYSMDVITSTSFGV 189
            :..||:.|...|:||::....::::....|.::  ::...||.:...::...::.:.:.....|:
  Fly   131 RHQRAVFSTLLTNGRIRTTHAIMQRVCLDLCQFIAIKSAGGKDLDCIDLGLRFTGESLFDCVLGI 195

  Rat   190 NVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVV-----LFPFLTPVYEMLNICMFPKDSIEFFKK 249
            ...:..:...|.|.:..::..    :...|::.     |||.|.   ..|...:||:....|:.:
  Fly   196 QARTFTDNPLPVVRQNHEMSA----ENRGLAIAGAVHGLFPNLP---RWLRPKVFPRSHDRFYGQ 253

  Rat   250 FVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIFIFAGYEPTSSTLS 314
            .:......| .|..:.|.||:       |...:.:....||:.::.:.::.|:|.|.:.||::::
  Fly   254 MISEALRLR-RSKHQERNDFI-------NHLLEMQRELDLSEEDMASHAMTFMFDGLDTTSNSIA 310

  Rat   315 FVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERVCKKD 379
            ..|..|..:||.|::|.||:....|....|..|.::::.||....||:||:||.|....:.|.|:
  Fly   311 HCLLLLGRNPDCQRRLYEELQLVNPGGYLPDLDALIDLPYLSACFNESLRIYPAGGWASKTCTKE 375

  Rat   380 VEING------VFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKEN-KGSIDPYVYLPFGNG 437
            .|:.|      :.:..|..||:|.||||.||..:|||:.||||||.... |......::|.||||
  Fly   376 YELRGSHHSEPLKLRPGDHVMVPIYALHNDPDLYPEPDVFRPERFLDGGLKNCKQQGIFLGFGNG 440

  Rat   438 PRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGLLQPTKPII----------LKV 492
            ||.|:|||..|...|.||..::|.|.......|....:|.         |:|          |:.
  Fly   441 PRQCVGMRLGLAMAKAALAAIVQRFEVVVSPRTLNGTELD---------PLIFVGVHKGGIWLQF 496

  Rat   493 VPRDEIIT 500
            |||..:.|
  Fly   497 VPRKNVTT 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	112/460 (24%)
Cyp28c1	NP_572752.1	CYP6-like	67..493	CDD:410679	112/457 (25%)