Protein Alignment Cyp3a23-3a1 and Cyp6a16

DIOPT Version :9

• Sequence 1: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Sequence 2: NP_001285631.1
• Gene: Cyp6a16 / 19836250
• FlyBaseID: FBgn0031726
• Length: 500
• Species: Drosophila melanogaster
• Alignment Length: 520
• Identity: 165/520 - (31%)
• Similarity: 264/520 - (50%)
• Gaps: 65/520 - (12%)

  Rat    11 TWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLN----YYMGLWKFDVECHKKYGKI 71
            |.:||..:|..|.|:.......::.:|||..:|...||....    :|..|.:...:..:...|:
  Fly     4 TLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSVHYSELLQETYDAFRGSAKV 68

  Rat    72 WGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGKAISVSKDEEWKRYRALLSPT 136
            .|.:....|:..:.|.:::|.||::: |:.|.:||.|....:.....:: :.|||:..|..||||
  Fly    69 AGTYVFLRPMAVVLDLDLVKAVLIRD-FNNFVDRRSFHGDPLTANLFNL-QGEEWRNLRTKLSPT 131

  Rat   137 FTSGRLKEMF----PVIEQYG---DILVKYLRQEKGKPVPVKEVFGAYSMDVITSTSFGVNVDSL 194
            ||||::|.||    .|.:|.|   |.||    ..:|..:.:.::...|:.|||.|.:||....||
  Fly   132 FTSGKMKYMFGTVSTVAQQLGGTFDELV----GSQGAVLELHDLMARYTTDVIGSCAFGTECSSL 192

  Rat   195 NNPKDPFVEKAKKL-------LRIDFFDPLFLSV---------VLFPFLTPVYEMLNICMFPKDS 243
            ..|:..|.:..:::       :|...|...:||.         :|.|.:|
  Fly   193 REPQAEFRQVGRRIFRNSNRSIRWRIFKMTYLSSLAKLGLPVRILHPDIT--------------- 242

  Rat   244 IEFFKKFVYRMKETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTALSDMEITAQSIIFIFAGYEP 308
             :||.:.|....|.| :.....|.||:.|::    |.:.:|:...|:..::.||:.:|..||:|.
  Fly   243 -KFFNRIVRETVELR-ERENIRRNDFMDLLL----DLRRQENGKGLTMEQMAAQAFVFFVAGFET 301

  Rat   309 TSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLE 373
            :||.:|:.|..||.:.|.|:||:.||:.::......||:.:|||.|||..:.||||.||..:.|.
  Fly   302 SSSNMSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLT 366

  Rat   374 RVCKKDVEI------NGVFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDPYVYL 432
            |:..:|.||      :.|.:.||:.|.||..|:|.||:.:|||.|||||||:.:......|..:|
  Fly   367 RLASEDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERFAPDACRERHPTAFL 431

  Rat   433 PFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQ--PCKETQIPLKLSRQGL-LQPTKPIILKVVP 494
            .||:|||||||:||..|.:|:.|..:|:.|.|.  |...||  ||::::.| |.|:..:.|:|.|
  Fly   432 GFGDGPRNCIGLRFGRMQVKVGLITLLRRFRFSLPPGSPTQ--LKVTKRNLILLPSDGVRLQVDP 494

  Rat   495  494
              Fly   495  494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	155/488 (32%)
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	155/488 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870