Protein Alignment GABRD and Rdl

DIOPT Version :9

• Sequence 1: XP_016856425.1
• Gene: GABRD / 2563
• HGNCID: 4084
• Length: 687
• Species: Homo sapiens
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 171/611 - (27%)
• Similarity: 250/611 - (40%)
• Gaps: 181/611 - (29%)

Human   223 PWPRCPEQCCIPRKGPRLSGIKLSPGLSDRWLCIPRAMNDIGDYVG-----------------SN 270
            |.||.|                    |...||.|..|:  |....|                 .:
  Fly    14 PLPRTP--------------------LLTIWLAINMAL--IAQETGHKRIHTVQAATGGGSMLGD 56

Human   271 LEISWLPNLDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRL 335
            :.||.:  ||.....|.:..||..|||||.|.:.:.|.||..:||..|::|:..:..|.|.|.||
  Fly    57 VNISAI--LDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMDFTLDFYFRQFWTDPRL 119

Human   336 SYNHTN--ETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 398
            :|....  |||.:.|.|:..:|:||||.||.|.::||..|..|:.||:...|.|..|||:|.|.:
  Fly   120 AYRKRPGVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITAS 184

Human   399 CDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNF 463
            |.|:|..:|||.|.|.:::||:||:..||.|:|.:....:....:::|.||.:..:|.....:|.
  Fly   185 CPMNLQYFPMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINL 249

Human   464 KSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTL 528
             :.|.:.||:......|:.|.|:||.|:||.|:|.:||||||:::.|.||||:||:|||||||||
  Fly   250 -TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTL 313

Human   529 MVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRPRAEMDVRN 593
            |.|..::||:.|.:|::|||...|:|.|||:|:|||...:.|...:.:|.:....:..||...:
  Fly   314 MSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKKQ- 377

Human   594 AIVLFSLSAAGVTQELAISRRQRRV--PGNL---------MGSYRSVGVETGETKKEGAAR---- 643
                   ...|..|:.|.......|  ||.:         .|...:|||..|...:.|...
  Fly   378 -------QLDGANQQQANPNPNANVGGPGGVGVGPGGPGGPGGGVNVGVGMGMGPEHGHGHGHHA 435

Human   644 --------------------------------------------------------------SGG 646
                                                                          :||
  Fly   436 HSHGHPHAPKQTVSNRPIGFSNIQQNVGTRGCSIVGPLFQEVRFKVHDPKAHSKGGTLENTVNGG 500

Human   647 QGGIRA----------------------------------------------------RLRPIDA 659
            :||.::                                                    :|..|..
  Fly   501 RGGPQSHGPGPGQGGGPPGGGGGGGGGGGPPEGGGDPEAAVPAHLLHPGKVKKVKDINKLLGITP 565

Human   660 DTIDIYARAVFPAAFAAVNVIYWAAY 685
            ..||.|:|.|||..|...|::||..|
  Fly   566 SDIDKYSRIVFPVCFVCFNLMYWIIY 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABRD	XP_016856425.1	None
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	65/183 (36%)
		Neur_chan_memb	274..588	CDD:397193	76/321 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D226476at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820