DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment OR4S1 and or90d2

DIOPT Version :9

Sequence 1:NP_001004725.1 Gene:OR4S1 / 256148 HGNCID:14705 Length:309 Species:Homo sapiens
Sequence 2:XP_021332980.1 Gene:or90d2 / 100113432 ZFINID:ZDB-GENE-070806-27 Length:309 Species:Danio rerio


Alignment Length:320 Identity:75/320 - (23%)
Similarity:123/320 - (38%) Gaps:55/320 - (17%)


- Green bases have known domain annotations that are detailed below.


Human    15 LFESREMQHTCFVVFFLFHVLTVLGNLLVIITINA-------RKTL--KSPMYFFLSQLSFADIC 70
            |:..:|.....|...|...:|.|     :||:||.       |:::  ..|.|.....|...|:.
Zfish     7 LYSQQERYADAFAKNFSIVLLAV-----IIISINGMFVFIFFRRSIFHSDPRYILYIHLVMNDML 66

Human    71 YPSTTIPKMIADTFVEHKI-ISFNGCMTQLFSAHFFGGTEIFLLTAMAYDRYVAICRPLHYTAIM 134
            ....::...:. ||..|.: :.|  |:..|.............|..||.:||:|:|:|||:..|.
Zfish    67 MVFISVVLFVM-TFAWHNVPVPF--CVLLLLITSVTHRNTPLTLAGMAIERYIAVCKPLHHHQIC 128

Human   135 DCRKCGLLAGASWLAGFLHSILQTLLTVQLPFCGPNEIDNFFCDVHPLLKLACADTYMVGLIVV- 198
            ..|...:|....|..|.|..:....|   |...||               ||...|....:|:. 
Zfish   129 TVRWTYMLISLIWSVGILPGLTDIFL---LLINGP---------------LALFTTICTSVILYN 175

Human   199 ---------ANSGMISLASFFILIISYVIILLNLR--SQSSEDRRKAVSTC---GSHVITVLLVL 249
                     .::|:.|...:.||:.:|..:::..:  |.:....:||.||.   |:.::..:|..
Zfish   176 TPSHAELSKISNGIYSSIVWLILVYTYCQVMVKAKRSSTNKSSAKKAQSTILLHGAQLLLCMLSY 240

Human   250 MPPMFMYIRPSTTLAADKLIILFNI----VMPPLLNPLIYTLRNNDVKNAMRKLFRVKRS 305
            :.|:...|.........|.|..||.    ::|.||.||||.:|:....|.::.|...|.|
Zfish   241 ITPVLDKIYAPLQTEQQKKINFFNYLLTSILPRLLTPLIYGVRDKQFFNHIKALLTCKLS 300

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OR4S1NP_001004725.1 7tm_4 29..303 CDD:304433 70/302 (23%)
7tm_1 39..285 CDD:278431 62/274 (23%)
or90d2XP_021332980.1 7tm_classA_rhodopsin-like 24..283 CDD:320086 66/284 (23%)
TM helix 1 24..45 CDD:320086 6/25 (24%)
TM helix 2 53..79 CDD:320086 3/26 (12%)
TM helix 3 89..119 CDD:320086 8/29 (28%)
TM helix 4 132..154 CDD:320086 4/21 (19%)
TM helix 5 179..204 CDD:320086 5/24 (21%)
TM helix 6 220..247 CDD:320086 7/26 (27%)
TM helix 7 258..283 CDD:320086 11/24 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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