Protein Alignment Oprm1 and AstC-R1

DIOPT Version :9

• Sequence 1: NP_001033690.1
• Gene: Oprm1 / 25601
• RGDID: 3234
• Length: 468
• Species: Rattus norvegicus
• Sequence 2: NP_649040.2
• Gene: AstC-R1 / 40020
• FlyBaseID: FBgn0036790
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 130/426 - (30%)
• Similarity: 206/426 - (48%)
• Gaps: 78/426 - (18%)

  Rat    45 LNRTGLGGNDSLCPQ-----TGSP----------SMVTAITIMALYSIVCVVGLFGNFLVMYVIV 94
            ||...:.|:.::.|:     |..|          |.....|:: ||..||::|||||.||:||::
  Fly    40 LNHRWISGSSTIQPEESLYGTDLPTYQHCIATRNSFADLFTVV-LYGFVCIIGLFGNTLVIYVVL 103

  Rat    95 RYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLC 159
            |::||:|.|||||.|||:||......:||......:.:|.||..:||..:.......|||...|.
  Fly   104 RFSKMQTVTNIYILNLAVADECFLIGIPFLLYTMRICSWRFGEFMCKAYMVSTSITSFTSSIFLL 168

  Rat   160 TMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHP 224
            .||.|||||||||:.:..:||...||:|:...|..|:.:.|||:..|:|..::..|:.:.....|
  Fly   169 IMSADRYIAVCHPISSPRYRTLHIAKVVSAIAWSTSAVLMLPVILYASTVEQEDGINYSCNIMWP 233

  Rat   225 TWYWEN---LLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSG--SKEKDRNLRRITRMVLV 284
            ..|.::   ...:..|...|..|:..|...|.|:|.:|:||....|  ||||.|..|::||:||.
  Fly   234 DAYKKHSGTTFILYTFFLGFATPLCFILSFYYLVIRKLRSVGPKPGTKSKEKRRAHRKVTRLVLT 298

  Rat   285 VVAVFIVCWTP--------IH--------------IYVIIKALITIPETTFQTVSWHFCIALGYT 327
            |::|:|:||.|        ||              |::::.||:                   |:
  Fly   299 VISVYILCWLPHWISQVALIHSNPAQRDLSRLEILIFLLLGALV-------------------YS 344

  Rat   328 NSCLNPVLYAFLDENFKRC-FREF-CI---PTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQP 387
            ||.:||:|||||.|||::. |:.| |:   ..::.::.:.|...:|.:::...:...:......|
  Fly   345 NSAVNPILYAFLSENFRKSFFKAFTCMNKQDINAQLQLEPSVFTKQGSKKRGGSKRLLTSNPQIP 409

  Rat   388 AL----------AVSVAQIFTGYPSPTHG-EKPCKS 412
            .|          :.:.:...|...:.|.| :|.|.|
  Fly   410 PLLPLNAGNNNSSTTTSSTTTAEKTGTTGTQKSCNS 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oprm1	NP_001033690.1	7tm_4	77..>281	CDD:304433	80/208 (38%)
		7tm_1	85..336	CDD:278431	94/277 (34%)
		NPxxY, plays a role in stabilizing the activated conformation of the receptor. /evidence=ECO:0000250|UniProtKB:P42866	332..336		2/3 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	361..385		2/23 (9%)
AstC-R1	NP_649040.2	7tm_4	88..368	CDD:304433	107/298 (36%)
		7tm_1	94..353	CDD:278431	94/277 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9091
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X22
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010