DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tnr and NimB4

DIOPT Version :9

Sequence 1:	NP_037177.2	Gene:	Tnr / 25567	RGDID:	3886	Length:	1358	Species:	Rattus norvegicus
Sequence 2:	NP_788046.1	Gene:	NimB4 / 34814	FlyBaseID:	FBgn0028542	Length:	448	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	86/355 - (24%)
Similarity:	123/355 - (34%)	Gaps:	114/355 - (32%)

- Green bases have known domain annotations that are detailed below.

  Rat    75 LESLC------------SSGLEASA-EQDVSAEDDTLAEYTGQ------TSDHE------SQVTF 114
            |.|||            ..|||... ||.:..:.|.......:      ..:||      |..|.
  Fly     5 LRSLCLHSVLLVLFLCVLHGLELQLHEQQLQQQKDEQLRLRAEQRQRELLREHEALQRRLSSSTT 69

  Rat   115 THK-------INLPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNTN--------CCQESA 164
            |.|       ::||::.   ....:..||:.:.....::||.::.:. :||        ||:
  Fly    70 TRKPYIIPNGLSLPRRG---EHPDKCRQEVPAVFFQYDKEVKIVGNS-STNPYMNVIEVCCK--- 127

  Rat   165 ATGQLDY-----VPHCS---GHGNFSFESCGCICNEGW---FGKNCSEPYCPLGCSSRGVCVDGQ 218
            ...:.:|     ||.|.   ....|......|:|...:   :..|| .|.|||||......::|.
  Fly   128 GWRRYEYDWSQCVPDCGERCQENGFCVAGGKCVCFTDFVLNYRNNC-VPTCPLGCPHGRCYLNGT 191

  Rat   219 CICDSEYSGDDCSEL---RCPTDCSSRGLCVD-GECVCEEPYTG---------------EDC--- 261
            |.||..|..|...:.   :|...|....:|:: |:|.|.|.||.               .||
  Fly   192 CQCDKGYELDGSRKFCQPQCNATCGHNEVCLEPGKCSCAEGYTRGLRESAALGCQPICIPDCGYG 256

  Rat   262 ------------------RELRCPGDC---SGKGQCAN-GTCLCQEGYAGEDCSQRRCLNACSGR 304
                              ..:.|.|||   ...|.||| .||:||.||. .|.:...||..|.
  Fly   257 HCVRPNECECFPGFQKRKNGITCEGDCYMTCENGFCANKTTCVCQNGYR-YDKNTTTCLPDCG-- 318

  Rat   305 GHCQEGLCI------CEEGY--QGPDCSAV 326
            .:|..|:||      |.:||  ....|.||
  Fly   319 DNCDNGVCISPGNCRCFKGYVRNRERCEAV 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tnr	NP_037177.2	exchanger_TraA	<190..>328	CDD:411343	54/192 (28%)
		EGF_Tenascin	203..231	CDD:376143	11/27 (41%)
		fn3	328..398	CDD:394996
		fn3	416..496	CDD:394996
		fn3	507..586	CDD:394996
		FN3	595..679	CDD:238020
		fn3	687..766	CDD:394996
		fn3	776..855	CDD:394996
		fn3	865..944	CDD:394996
		fn3	954..1026	CDD:394996
		FN3	1042..1127	CDD:238020
		FReD	1134..1342	CDD:238040
NimB4	NP_788046.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910