DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc2a3 and sut2

DIOPT Version :9

Sequence 1:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus
Sequence 2:	NP_524732.1	Gene:	sut2 / 44269	FlyBaseID:	FBgn0028562	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	475	Identity:	153/475 - (32%)
Similarity:	254/475 - (53%)	Gaps:	9/475 - (1%)

- Green bases have known domain annotations that are detailed below.

  Rat     9 TPSLVFAVTVATIG-SFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTLWSLCVAIF 72
            ||.|:......|:| :...||..||:|||..|||.:....|....:.:.:.|.|..||:..|:|:
  Fly    16 TPLLMLICLTVTLGTTIPVGYFFGVLNAPAEIIKKWCQDILANEYDTIVTAGQLDILWTSIVSIY 80

  Rat    73 SVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCT 137
            .:||:.||....:..:::||:..:::.:::.::.|.|..:.:.|:|:|||:.||.:.||...|..
  Fly    81 LIGGICGSCFSAVLCDKYGRKGCLVISSVLFVVSGILFTWCRAAKSLEMLMTGRFLGGIASALIF 145

  Rat   138 GFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSA 202
            ...|||:.|.:|:.|.|:.|....:|:..|||:|||..|..:||||.|||..|....:..:....
  Fly   146 TAQPMYLLESAPSELSGSVGVFTCIGVTGGILLAQVATLSHLLGSERLWPYALSFYSLLVMASLV 210

  Rat   203 ALPFCPESPRFLLINRKEEDQATEILQRLWG---TPDVIQEIQEMKDESIRMSQEKQVTVLELFK 264
            .|.:.|||||:|.:::::...:.:.|.||.|   ..:|.||:.|||......|..:..::..:.:
  Fly   211 LLWWFPESPRWLYLHKRDSAASEKALLRLRGRNTEEEVHQELLEMKATLEAKSSSEVSSLCSVLR 275

  Rat   265 SPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQE--PIYATIGAGVVNTIFTVVSLFL 327
            :...:.|||:....|.:||.|||||:|:||..|..:||..:  ..:..:|.|..|...:::...|
  Fly   276 NSELWLPLLLVCSFQATQQLSGINAIFFYSLSILTNAGFSDGAATWLNLGIGSFNLCTSLLGPLL 340

  Rat   328 VERAGRRTLHMIGLGGMAVCSVFMTISL--LLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFI 390
            :.|..||.|.||.....|:..:.|::.|  |.:.|...:::.|...||.::..|::|.|||.:||
  Fly   341 IRRFPRRPLMMISCSMCALALLAMSLGLFFLERSESTVLTYFCAAFILTFILGFQLGLGPIAYFI 405

  Rat   391 VAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTFFKVPET 455
            .:||....|||.||::....:|..||||||.||...:...::.||......::.|:.|:..:|||
  Fly   406 GSELLEDSPRPVAMSMGSLFSWIGNFLVGMCFPLLQSVWSSFAFIPCMCVCIYCLLLTWRYLPET 470

  Rat   456 KGRTFEDITRAFEGQAQSGK 475
            :||..:|: :....|..|.|
  Fly   471 RGREPKDV-KLLMSQGLSSK 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	147/459 (32%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	141/441 (32%)
sut2	NP_524732.1	Sugar_tr	23..473	CDD:278511	144/449 (32%)
sut2	NP_524732.1	MFS	76..466	CDD:119392	124/389 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337760
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.800