DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Slc2a3 and CG1213

DIOPT Version :9

Sequence 1:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus
Sequence 2:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	488	Identity:	136/488 - (27%)
Similarity:	218/488 - (44%)	Gaps:	43/488 - (8%)

- Green bases have known domain annotations that are detailed below.

  Rat     2 ESNKQNVTPS------LVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGL 60
            |.|.:.::|.      :..|...|.:.:|..|...|..:.....:|       .|...|.|....
  Fly    26 EGNTRTMSPEPVKSGRIFMAAVAANLSAFVVGTTLGWTSPIGPKLK-------SEDTSDSPLSRP 83

  Rat    61 LTT---LWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEML 122
            :|:   .|  ..::.:||.::..|..|...:|.||:..:|..:|..:|.   .|...:|..|.:|
  Fly    84 ITSDEDAW--ISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLA---FGLNMVASEVWIL 143

  Rat   123 ILGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWP 187
            .:.|||.|...|......|||:||:|...:|||.|:|.||.||.|||..      :.:|....:.
  Fly   144 YMSRLIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYV------YAIGPYVSYQ 202

  Rat   188 GLLGLTIIPAILQSAALPFCPESPRFLLINRKEEDQATEILQRL-----WGTPDVIQEIQEMKDE 247
            .|....|:..::........||||.| ...:..:.:|.:.||.|     .|..|.:.|||...:|
  Fly   203 ALQWCCIVVPVVFDLVFYMMPESPYF-FAGKGRKSEALKSLQFLRGQSAEGVHDEMAEIQANVEE 266

  Rat   248 SIRMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGV-QEPIYATI 311
            ::    ..:.||::|||:....:.|.|...|...||.||||.|.:.|..||..|.. .:|..|||
  Fly   267 AM----ASKGTVMDLFKNAGNRRALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATI 327

  Rat   312 GAGVVNTIFTVVSLFLVERAGRRTLHMIGLG----GMAVCSVFMTISLLLKDEYEAMSFVCIVAI 372
            ..|.|....:.::..:.:|.||:.:.:....    |:|....|..:. |:|.:..::.::.:.|:
  Fly   328 IIGCVQVGSSALTPLVADRLGRKVMLLTSSSVMSIGLAALGAFFYMQ-LVKGDISSVVWMPVPAL 391

  Rat   373 LVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIF 437
            ::|...:..|.||:||.::.|:|....:..|.:|...:.||..|||..|:||..|....|.|.:|
  Fly   392 IIYNIVYCTGFGPLPWAVLGEMFPANIKSVASSVVASTCWTLGFLVTFFYPSLDALGSYYAFWLF 456

  Rat   438 AAFLVFFLIFTFFKVPETKGRTFEDITRAFEGQ 470
            |..:|....|..|.|.||||.:.:.|.....|:
  Fly   457 AVCMVVAFFFVLFVVMETKGLSLQQIQDRLNGK 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	132/464 (28%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	124/446 (28%)
CG1213	NP_001246937.1	SP	42..482	CDD:273317	131/463 (28%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	122/436 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810